BS8418

antibody from Bioworld Technology, Inc
Targeting: TAGLN DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10
Provider product page for BS8418
Western blot
Immunohistochemistry

Antibody data

Product number
BS8418 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TAGLN polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TAGLN.
Description
Transgelin, also designated SM22a, is expressed abundantly in smooth muscle cells. The human transgelin gene (designated TAGLN), which is located on chromosome 11q23.3, encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is downregulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TAGLN protein structure - BS8418 shown in red.