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- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Flow cytometry [1]
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- Product number
- 342202 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#342202, RRID:AB_1626134
- Product name
- Purified anti-human CD205 (DEC-205)
- Antibody type
- Monoclonal
- Antigen
- CD205 (DEC-205)
- Description
- CD205 is a 210 kD C-type lectin transmembrane protein, known as DEC-205. It belongs to macrophage mannose receptor family and is found at high levels on dendritic cells and thymic epithelial cells. Unlike murine CD205, human CD205 is also expressed at low levels on T- and B-cells, NK cells and monocytes. CD205, serves as an endocytic receptor, functions in antigen uptake/processing and clearance of apoptotic cells.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses.
Gurer C, Strowig T, Brilot F, Pack M, Trumpfheller C, Arrey F, Park CG, Steinman RM, Münz C
Blood 2008 Aug 15;112(4):1231-9
Blood 2008 Aug 15;112(4):1231-9
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Monocyte-derived dendritic cells stained with HD30 PE
- Conjugate
- Unconjugated
