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LearnTissue expression
Cell line expression
Protein structure
BCL2L2
BCL2 like 2BCL-W, KIAA0271, PPP1R51
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-78865 |
1 references | Polyclonal |
WB
IHC
FC
OA
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| antibodies-online | ABIN5682487 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| Novus Biologicals | NBP2-61706 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| Proteintech Group | 16026-1-AP |
3 references | Polyclonal |
WB
EL
IHC
|
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| Enzo Life Sciences | ALX-804-353-C100 |
4 references | Monoclonal |
WB
ICC
IP
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