BS6021

antibody from Bioworld Technology, Inc
Targeting: BCL2L13 BCL-RAMBO, MIL1
Provider product page for BS6021
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6021 - Provider product page
Provider
Bioworld Technology, Inc
Product name
BCL2L13 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human BCL2L13.
Description
The Bcl-2 family of proteins plays a central regulatory role in apoptosis. Bcl-rambo, a member of the Bcl-2 family, localizes to the mitochondria and, like other Bcl-2 family members, contains all four BH domains. Although Bcl-rambo shares structural similarity to other Bcl-2 members, it differs from them in its unique C-terminal region. Bcl-rambo has a 250 amino acid sequence containing two tandem repeats that preceeds the membrane anchor region at its C-terminus. Additionally, it is the membrane anchor C-terminal region of Bcl-rambo, not its Bcl-2 homology motifs, that is responsible for its pro-apoptotic activity. Bcl-rambo induces apoptosis when overexpressed and appears to do so by promoting mitochondrial cyto-chrome c release. It may also facilitate the activation of caspase-3.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BCL2L13 protein structure - BS6021 shown in red.