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LearnTissue expression
Cell line expression
Protein structure
SPP1
Secreted phosphoprotein 1BNSP, BSPI, ETA-1, OPN
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Top validated antibodies |
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| R&D Systems |  AF808 |
71 references | Polyclonal |
WB
EL
ICC
IHC
BN
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| Proteintech Group | 22952-1-AP |
91 references | Polyclonal |
WB
EL
ICC
IHC
FC
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| GeneTex | GTX28448 |
4 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Novus Biologicals | AF1433 |
17 references | Polyclonal |
EL
ICC
IHC
BN
|
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| OriGene | R1565 |
1 references | Polyclonal |
WB
EL
IP
IHC
OA
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