Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [91]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 22952-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22952-1-AP, RRID:AB_2783651
- Product name
- Osteopontin antibody
- Antibody type
- Polyclonal
- Description
- Osteopontin antibody (Cat. #22952-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Bioinformatics analysis of laryngeal squamous cell carcinoma: seeking key candidate genes and pathways.
Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.
FBS-Derived Exosomes as a Natural Nano-Scale Carrier for Icariin Promote Osteoblast Proliferation.
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
Metformin Inhibits Abdominal Aortic Aneurysm Formation through the Activation of the AMPK/mTOR Signaling Pathway.
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Identification of VWF as a Novel Biomarker in Lung Adenocarcinoma by Comprehensive Analysis.
Exogenous H2 S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Biomimetic Cell-Substrate of Chitosan-Cross-linked Polyaniline Patterning on TiO2 Nanotubes Enables hBM-MSCs to Differentiate the Osteoblast Cell Type.
Polydopamine-Coated Poly(l-lactide) Nanofibers with Controlled Release of VEGF and BMP-2 as a Regenerative Periosteum.
Association of urinary ketamine and APOA1 levels with bladder dysfunction in ketamine abusers revealed via proteomics and targeted metabolite analyses.
Primary cilia regulate gastric cancer-induced bone loss via cilia/Wnt/β-catenin signaling pathway.
Inactivation of SERCA2 Cys674 accelerates aortic aneurysms by suppressing PPARγ.
Long-lasting renewable antibacterial porous polymeric coatings enable titanium biomaterials to prevent and treat peri-implant infection.
The preventive and therapeutic effects of AAV1-KLF4-shRNA in cigarette smoke-induced pulmonary hypertension.
A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma.
A Dual Role of Heme Oxygenase-1 in Angiotensin II-Induced Abdominal Aortic Aneurysm in the Normolipidemic Mice.
Significance of MR/OPN/HMGB1 axis in NAFLD-associated hepatic fibrogenesis.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Establishment and characterization of a highly metastatic human osteosarcoma cell line from osteosarcoma lung metastases.
Semaphorin3A promotes osseointegration of titanium implants in osteoporotic rabbits.
Polo Like Kinase 4 (PLK4) impairs human bone marrow mesenchymal stem cell (BMSC) viability and osteogenic differentiation.
Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging.
Piperlongumine Attenuates High Calcium/Phosphate-Induced Arterial Calcification by Preserving P53/PTEN Signaling.
Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Suppresses Migration of Bone-Metastatic Breast Cancer Cells via OPN-FAK/ERK/NF-κB Axis.
OPN Deficiency Increases the Severity of Osteoarthritis Associated with Aberrant Chondrocyte Senescence and Apoptosis and Upregulates the Expression of Osteoarthritis-Associated Genes.
R-Spondin 2 Induces Odontogenic Differentiation of Dental Pulp Stem/Progenitor Cells via Regulation of Wnt/β-Catenin Signaling.
Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway.
RNA-seq analysis of palatal transcriptome changes in all-trans retinoic acid-induced cleft palate of mice.
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
T-cell death-associated gene 8 accelerates atherosclerosis by promoting vascular smooth muscle cell proliferation and migration.
Exercise Promotes the Osteoinduction of HA/β-TCP Biomaterials via the Wnt Signaling Pathway.
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Quantitative alterations in bovine milk proteome from healthy, subclinical and clinical mastitis during S. aureus infection.
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
The effect of extracellular matrix on the differentiation of mouse embryonic stem cells.
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Modulation of the mechanosensing of mesenchymal stem cells by laser-induced patterning for the acceleration of tissue reconstruction through the Wnt/β-catenin signaling pathway activation.
SHED-derived conditioned exosomes enhance the osteogenic differentiation of PDLSCs via Wnt and BMP signaling in vitro.
P38 MAPK signaling pathway mediates COM crystal-induced crystal adhesion change in rat renal tubular epithelial cells.
Semaphorin 3A-hypoxia inducible factor 1 subunit alpha co-overexpression enhances the osteogenic differentiation of induced pluripotent stem cells-derived mesenchymal stem cells in vitro.
PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission.
Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Biomineralizaion of hydroxyapatite on polyethylene terephthalate artificial ligaments promotes graft-bone healing after anterior cruciate ligament reconstruction: An in vitro and in vivo study.
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Effect of interleukin-33 on cementoblast-mediated cementum repair during orthodontic tooth movement.
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways.
2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes injury-induced vascular neointima formation in mice.
Inhibiting effect of microRNA-187-3p on osteogenic differentiation of osteoblast precursor cells by suppressing cannabinoid receptor type 2.
Incorporated-bFGF polycaprolactone/polyvinylidene fluoride nanocomposite scaffold promotes human induced pluripotent stem cells osteogenic differentiation.
SPARC induces phenotypic modulation of human brain vascular smooth muscle cells via AMPK/mTOR-mediated autophagy.
Osteopontin in the Pathogenesis of Aortic Dissection by the Enhancement of MMP Expressions.
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Adipose-derived stem cells-conditioned medium improved osteogenic differentiation of induced pluripotent stem cells when grown on polycaprolactone nanofibers.
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress.
Circulating osteopontin per tumor volume as a prognostic biomarker for resectable intrahepatic cholangiocarcinoma.
Effect of Hydroxyapatite Nanorods on the Fate of Human Adipose-Derived Stem Cells Assessed In Situ at the Single Cell Level with a High-Throughput, Real-Time Microfluidic Chip.
Efficient osteogenic differentiation of the dental pulp stem cells on β-glycerophosphate loaded polycaprolactone/polyethylene oxide blend nanofibers.
Quantitative proteomics of milk whey reveals breed and season specific variation in protein abundance in Holstein Friesian cow and Murrah buffalo.
Effect of microRNA-21 on hypoxia-inducible factor-1α in orthodontic tooth movement and human periodontal ligament cells under hypoxia.
Promoting osteogenic differentiation of human-induced pluripotent stem cells by releasing Wnt/β-catenin signaling activator from the nanofibers.
New Application of Psoralen and Angelicin on Periodontitis With Anti-bacterial, Anti-inflammatory, and Osteogenesis Effects.
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.
Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.
Hypoxia-Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis.
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
Negative pressure wound therapy promotes muscle-derived stem cell osteogenic differentiation through MAPK pathway.
Teniposide regulates the phenotype switching of vascular smooth muscle cells in a miR-21-dependent manner.
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.
Osteopontin contributes to effective neutrophil recruitment, IL-1β production and apoptosis in Aspergillus fumigatus keratitis.
The prognostic value of osteopontin in limited-stage small cell lung cancer patients and its mechanism.
The protective effect of PFTα on alcohol-induced osteonecrosis of the femoral head.
MgAl layered double hydroxide/chitosan porous scaffolds loaded with PFTα to promote bone regeneration.
Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines.
Transcriptome analysis in primary colorectal cancer tissues from patients with and without liver metastases using next-generation sequencing.
MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin.
Interleukin-6 enhances cancer stemness and promotes metastasis of hepatocellular carcinoma via up-regulating osteopontin expression.
Intrarenal macrophage infiltration induced by T cells is associated with podocyte injury in lupus nephritis patients.
Comparative investigation of human amniotic epithelial cells and mesenchymal stem cells for application in bone tissue engineering.
The chemokine CXCL13 in lung cancers associated with environmental polycyclic aromatic hydrocarbons pollution.
Serum anti-osteopontin autoantibody as a novel diagnostic and prognostic biomarker in patients with hepatocellular carcinoma.
Protective effects of epigallocatechin gallate (EGCG) on streptozotocin-induced diabetic nephropathy in mice.
Characterization of a micro-roughened TiO2/ZrO2 coating: mechanical properties and HBMSC responses in vitro.
Osteogenic differentiation of human amniotic epithelial cells and its application in alveolar defect restoration.
Ma J, Hu X, Dai B, Wang Q, Wang H
PeerJ 2021;9:e11259
PeerJ 2021;9:e11259
Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis.
Xu Y, Xin R, Sun H, Long D, Li Z, Liao H, Xue T, Zhang Z, Kang Y, Mao G
Frontiers in cell and developmental biology 2021;9:723759
Frontiers in cell and developmental biology 2021;9:723759
FBS-Derived Exosomes as a Natural Nano-Scale Carrier for Icariin Promote Osteoblast Proliferation.
Dong M, Wu S, Xu H, Yu X, Wang L, Bai H, Niu W
Frontiers in bioengineering and biotechnology 2021;9:615920
Frontiers in bioengineering and biotechnology 2021;9:615920
PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.
Li J, Wang C, Wang W, Liu L, Zhang Q, Zhang J, Wang B, Wang S, Hou L, Gao C, Yu X, Sun L
Frontiers in cardiovascular medicine 2021;8:624796
Frontiers in cardiovascular medicine 2021;8:624796
Metformin Inhibits Abdominal Aortic Aneurysm Formation through the Activation of the AMPK/mTOR Signaling Pathway.
He J, Li N, Fan Y, Zhao X, Liu C, Hu X
Journal of vascular research 2021;58(3):148-158
Journal of vascular research 2021;58(3):148-158
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Dong XH, Zhang MZ, Lai CZ, Li CC, Du L, Song GD, Zong XL, Jin XL
American journal of translational research 2021;13(10):11255-11270
American journal of translational research 2021;13(10):11255-11270
Identification of VWF as a Novel Biomarker in Lung Adenocarcinoma by Comprehensive Analysis.
He Y, Liu R, Yang M, Bi W, Zhou L, Zhang S, Jin J, Liang X, Zhang P
Frontiers in oncology 2021;11:639600
Frontiers in oncology 2021;11:639600
Exogenous H2 S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Biomimetic Cell-Substrate of Chitosan-Cross-linked Polyaniline Patterning on TiO2 Nanotubes Enables hBM-MSCs to Differentiate the Osteoblast Cell Type.
Kandel R, Jang SR, Shrestha S, Lee SY, Shrestha BK, Park CH, Kim CS
ACS applied materials & interfaces 2021 Oct 6;13(39):47100-47117
ACS applied materials & interfaces 2021 Oct 6;13(39):47100-47117
Polydopamine-Coated Poly(l-lactide) Nanofibers with Controlled Release of VEGF and BMP-2 as a Regenerative Periosteum.
Sun H, Dong J, Wang Y, Shen S, Shi Y, Zhang L, Zhao J, Sun X, Jiang Q
ACS biomaterials science & engineering 2021 Oct 11;7(10):4883-4897
ACS biomaterials science & engineering 2021 Oct 11;7(10):4883-4897
Association of urinary ketamine and APOA1 levels with bladder dysfunction in ketamine abusers revealed via proteomics and targeted metabolite analyses.
Liu JC, Chen YT, Hsieh YJ, Wu CC, Huang MC, Hsu YC, Wu CT, Chen CK, Dash S, Yu JS
Scientific reports 2021 May 5;11(1):9583
Scientific reports 2021 May 5;11(1):9583
Primary cilia regulate gastric cancer-induced bone loss via cilia/Wnt/β-catenin signaling pathway.
Xu J, Deng X, Wu X, Zhu H, Zhu Y, Liu J, Chen Q, Yuan C, Liu G, Wang C
Aging 2021 Mar 9;13(6):8989-9010
Aging 2021 Mar 9;13(6):8989-9010
Inactivation of SERCA2 Cys674 accelerates aortic aneurysms by suppressing PPARγ.
Que Y, Shu X, Wang L, Wang S, Li S, Hu P, Tong X
British journal of pharmacology 2021 Jun;178(11):2305-2323
British journal of pharmacology 2021 Jun;178(11):2305-2323
Long-lasting renewable antibacterial porous polymeric coatings enable titanium biomaterials to prevent and treat peri-implant infection.
Wu S, Xu J, Zou L, Luo S, Yao R, Zheng B, Liang G, Wu D, Li Y
Nature communications 2021 Jun 3;12(1):3303
Nature communications 2021 Jun 3;12(1):3303
The preventive and therapeutic effects of AAV1-KLF4-shRNA in cigarette smoke-induced pulmonary hypertension.
Sun D, Ding D, Li Q, Xie M, Xu Y, Liu X
Journal of cellular and molecular medicine 2021 Jan;25(2):1238-1251
Journal of cellular and molecular medicine 2021 Jan;25(2):1238-1251
A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma.
Tan X, Shi L, Banerjee P, Liu X, Guo HF, Yu J, Bota-Rabassedas N, Rodriguez BL, Gibbons DL, Russell WK, Creighton CJ, Kurie JM
The Journal of clinical investigation 2021 Jan 4;131(1)
The Journal of clinical investigation 2021 Jan 4;131(1)
A Dual Role of Heme Oxygenase-1 in Angiotensin II-Induced Abdominal Aortic Aneurysm in the Normolipidemic Mice.
Kopacz A, Klóska D, Werner E, Hajduk K, Grochot-Przęczek A, Józkowicz A, Piechota-Polańczyk A
Cells 2021 Jan 15;10(1)
Cells 2021 Jan 15;10(1)
Significance of MR/OPN/HMGB1 axis in NAFLD-associated hepatic fibrogenesis.
Tang M, Jia H, Chen S, Yang B, Patpur BK, Song W, Chang Y, Li J, Yang C
Life sciences 2021 Jan 1;264:118619
Life sciences 2021 Jan 1;264:118619
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
Li Z, Luo W, Fang S, Chen X, Lin T, Zhou S, Zhang L, Yang W, Li Z, Ye J, Wang J, Liu P, Li Z
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Xin D, Li T, Chu X, Ke H, Liu D, Wang Z
Pharmacological research 2021 Feb;164:105322
Pharmacological research 2021 Feb;164:105322
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Wang J, Hu X, Hu X, Gao F, Li M, Cui Y, Wei X, Qin Y, Zhang C, Zhao Y, Gao Y
The international journal of biochemistry & cell biology 2021 Feb;131:105873
The international journal of biochemistry & cell biology 2021 Feb;131:105873
Establishment and characterization of a highly metastatic human osteosarcoma cell line from osteosarcoma lung metastases.
Fan Z, Huang G, Zhao J, Li W, Lin T, Su Q, Yin J, Shen J
Journal of bone oncology 2021 Aug;29:100378
Journal of bone oncology 2021 Aug;29:100378
Semaphorin3A promotes osseointegration of titanium implants in osteoporotic rabbits.
Song A, Jiang F, Wang Y, Wang M, Wu Y, Zheng Y, Song X, Zhang W, Zhou J
Clinical oral investigations 2021 Aug 6;
Clinical oral investigations 2021 Aug 6;
Polo Like Kinase 4 (PLK4) impairs human bone marrow mesenchymal stem cell (BMSC) viability and osteogenic differentiation.
Zhou B, Peng K, Wang G, Chen W, Kang Y
Biochemical and biophysical research communications 2021 Apr 16;549:221-228
Biochemical and biophysical research communications 2021 Apr 16;549:221-228
Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging.
Dai G, Li Y, Liu J, Zhang C, Chen M, Lu P, Rui Y
Frontiers in cell and developmental biology 2020;8:570605
Frontiers in cell and developmental biology 2020;8:570605
Piperlongumine Attenuates High Calcium/Phosphate-Induced Arterial Calcification by Preserving P53/PTEN Signaling.
Shi W, Lu J, Li J, Qiu M, Lu Y, Gu J, Kong X, Sun W
Frontiers in cardiovascular medicine 2020;7:625215
Frontiers in cardiovascular medicine 2020;7:625215
Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Suppresses Migration of Bone-Metastatic Breast Cancer Cells via OPN-FAK/ERK/NF-κB Axis.
Fang T, Yan YX, Yang Y, Lv YX, Chang QQ, Zhang DD
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3573240
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3573240
OPN Deficiency Increases the Severity of Osteoarthritis Associated with Aberrant Chondrocyte Senescence and Apoptosis and Upregulates the Expression of Osteoarthritis-Associated Genes.
Tian J, Cheng C, Kuang SD, Su C, Zhao X, Xiong YL, Li YS, Gao SG
Pain research & management 2020;2020:3428587
Pain research & management 2020;2020:3428587
R-Spondin 2 Induces Odontogenic Differentiation of Dental Pulp Stem/Progenitor Cells via Regulation of Wnt/β-Catenin Signaling.
Gong Y, Yuan S, Sun J, Wang Y, Liu S, Guo R, Dong W, Li R
Frontiers in physiology 2020;11:918
Frontiers in physiology 2020;11:918
Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway.
Zhang X, Huang F, Chen X, Wu X, Zhu J
Drug development research 2020 Nov;81(7):875-884
Drug development research 2020 Nov;81(7):875-884
RNA-seq analysis of palatal transcriptome changes in all-trans retinoic acid-induced cleft palate of mice.
Peng Y, Wang XH, Su CN, Qiao WW, Gao Q, Sun XF, Meng LY
Environmental toxicology and pharmacology 2020 Nov;80:103438
Environmental toxicology and pharmacology 2020 Nov;80:103438
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Wang L, Muneer A, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Gheorghe C, Torralba K, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
bioRxiv : the preprint server for biology 2020 Nov 16;
bioRxiv : the preprint server for biology 2020 Nov 16;
T-cell death-associated gene 8 accelerates atherosclerosis by promoting vascular smooth muscle cell proliferation and migration.
Chen LD, Zhu WT, Cheng YY, Li ZH, Chen YQ, Yuan ZW, Lin CY, Jing DD, Liu ZQ, Yan PK
Atherosclerosis 2020 Mar;297:64-73
Atherosclerosis 2020 Mar;297:64-73
Exercise Promotes the Osteoinduction of HA/β-TCP Biomaterials via the Wnt Signaling Pathway.
Cheng L, Khalaf AT, Lin T, Ran L, Shi Z, Wan J, Zhou X, Zou L
Metabolites 2020 Mar 5;10(3)
Metabolites 2020 Mar 5;10(3)
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Wang Y, Zhang X, Chen W, Gao L, Li J, Song T, Chi J, Zhang X, Shi Z, Dong Y, Yin X, Liu Y
Life sciences 2020 Jul 15;253:117726
Life sciences 2020 Jul 15;253:117726
Quantitative alterations in bovine milk proteome from healthy, subclinical and clinical mastitis during S. aureus infection.
Maity S, Das D, Ambatipudi K
Journal of proteomics 2020 Jul 15;223:103815
Journal of proteomics 2020 Jul 15;223:103815
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
Wang L, Yu P, Zhou B, Song J, Li Z, Zhang M, Guo G, Wang Y, Chen X, Han L, Hu S
Nature cell biology 2020 Jan;22(1):108-119
Nature cell biology 2020 Jan;22(1):108-119
The effect of extracellular matrix on the differentiation of mouse embryonic stem cells.
Ozdil B, Güler G, Acikgoz E, Kocaturk DC, Aktug H
Journal of cellular biochemistry 2020 Jan;121(1):269-283
Journal of cellular biochemistry 2020 Jan;121(1):269-283
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Xu A, Yang Y, Shao Y, Wu M, Sun Y
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
Modulation of the mechanosensing of mesenchymal stem cells by laser-induced patterning for the acceleration of tissue reconstruction through the Wnt/β-catenin signaling pathway activation.
Fu J, Liu X, Tan L, Cui Z, Liang Y, Li Z, Zhu S, Zheng Y, Kwok Yeung KW, Chu PK, Wu S
Acta biomaterialia 2020 Jan 1;101:152-167
Acta biomaterialia 2020 Jan 1;101:152-167
SHED-derived conditioned exosomes enhance the osteogenic differentiation of PDLSCs via Wnt and BMP signaling in vitro.
Wang M, Li J, Ye Y, He S, Song J
Differentiation; research in biological diversity 2020 Jan - Feb;111:1-11
Differentiation; research in biological diversity 2020 Jan - Feb;111:1-11
P38 MAPK signaling pathway mediates COM crystal-induced crystal adhesion change in rat renal tubular epithelial cells.
Qi S, Wang Q, Xie B, Chen Y, Zhang Z, Xu Y
Urolithiasis 2020 Feb;48(1):9-18
Urolithiasis 2020 Feb;48(1):9-18
Semaphorin 3A-hypoxia inducible factor 1 subunit alpha co-overexpression enhances the osteogenic differentiation of induced pluripotent stem cells-derived mesenchymal stem cells in vitro.
Li JY, Wang TT, Li C, Wang ZF, Li S, Ma L, Zheng LL
Chinese medical journal 2020 Feb 5;133(3):301-309
Chinese medical journal 2020 Feb 5;133(3):301-309
PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission.
Guo J, Ren R, Yao X, Ye Y, Sun K, Lin J, Wang G, Guo F, Xiao J, Xu T
Aging 2020 Feb 25;12(4):3976-3992
Aging 2020 Feb 25;12(4):3976-3992
Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.
Wang Y, Chen J, Chen J, Dong C, Yan X, Zhu Z, Lu P, Song Z, Liu H, Chen S
Toxicology and applied pharmacology 2020 Dec 15;409:115333
Toxicology and applied pharmacology 2020 Dec 15;409:115333
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Yu W, Xiao L, Que Y, Li S, Chen L, Hu P, Xiong R, Seta F, Chen H, Tong X
Biochimica et biophysica acta. Molecular basis of disease 2020 Dec 1;1866(12):165912
Biochimica et biophysica acta. Molecular basis of disease 2020 Dec 1;1866(12):165912
Biomineralizaion of hydroxyapatite on polyethylene terephthalate artificial ligaments promotes graft-bone healing after anterior cruciate ligament reconstruction: An in vitro and in vivo study.
Cai J, Ai C, Chen J, Chen S
Journal of biomaterials applications 2020 Aug;35(2):193-204
Journal of biomaterials applications 2020 Aug;35(2):193-204
AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Si Y, Huang J, Li X, Fu Y, Xu R, Du Y, Cheng J, Jiang H
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Cell communication and signaling : CCS 2020 Aug 31;18(1):139
Effect of interleukin-33 on cementoblast-mediated cementum repair during orthodontic tooth movement.
Dong X, Feng J, Wen J, Bai D, Xu H
Archives of oral biology 2020 Apr;112:104663
Archives of oral biology 2020 Apr;112:104663
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Tian L, Xiao H, Li M, Wu X, Xie Y, Zhou J, Zhang X, Wang B
Metabolism: clinical and experimental 2020 Apr;105:154189
Metabolism: clinical and experimental 2020 Apr;105:154189
Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways.
Yao X, Jing X, Guo J, Sun K, Deng Y, Zhang Y, Guo F, Ye Y
Frontiers in pharmacology 2019;10:163
Frontiers in pharmacology 2019;10:163
2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes injury-induced vascular neointima formation in mice.
Guo S, Zhang R, Liu Q, Wan Q, Wang Y, Yu Y, Liu G, Shen Y, Yu Y, Zhang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10207-10217
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10207-10217
Inhibiting effect of microRNA-187-3p on osteogenic differentiation of osteoblast precursor cells by suppressing cannabinoid receptor type 2.
Xu A, Yang Y, Shao Y, Wu M, Sun Y
Differentiation; research in biological diversity 2019 Sep - Oct;109:9-15
Differentiation; research in biological diversity 2019 Sep - Oct;109:9-15
Incorporated-bFGF polycaprolactone/polyvinylidene fluoride nanocomposite scaffold promotes human induced pluripotent stem cells osteogenic differentiation.
Abazari MF, Soleimanifar F, Enderami SE, Nematzadeh M, Nasiri N, Nejati F, Saburi E, Khodashenas S, Darbasizadeh B, Khani MM, Ghoraeian P
Journal of cellular biochemistry 2019 Oct;120(10):16750-16759
Journal of cellular biochemistry 2019 Oct;120(10):16750-16759
SPARC induces phenotypic modulation of human brain vascular smooth muscle cells via AMPK/mTOR-mediated autophagy.
Li T, Tan X, Zhu S, Zhong W, Huang B, Sun J, Li F, Wang Y
Neuroscience letters 2019 Nov 1;712:134485
Neuroscience letters 2019 Nov 1;712:134485
Osteopontin in the Pathogenesis of Aortic Dissection by the Enhancement of MMP Expressions.
Fan F, Zhou Q, Xu Z, Wang D
International heart journal 2019 Mar 20;60(2):429-435
International heart journal 2019 Mar 20;60(2):429-435
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
Wang S, Xu C, Yu S, Wu X, Jie Z, Dai H
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
Xue K, Zhang J, Li C, Li J, Wang C, Zhang Q, Chen X, Yu X, Sun L, Yu X
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Shi A, Heinayati A, Bao D, Liu H, Ding X, Tong X, Wang L, Wang B, Qin H
Stem cell research & therapy 2019 Jun 13;10(1):172
Stem cell research & therapy 2019 Jun 13;10(1):172
Adipose-derived stem cells-conditioned medium improved osteogenic differentiation of induced pluripotent stem cells when grown on polycaprolactone nanofibers.
Soleimanifar F, Hosseini FS, Atabati H, Behdari A, Kabiri L, Enderami SE, Khani MM, Ardeshirylajimi A, Saburi E
Journal of cellular physiology 2019 Jul;234(7):10315-10323
Journal of cellular physiology 2019 Jul;234(7):10315-10323
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress.
Feng H, Wang JY, Yu B, Cong X, Zhang WG, Li L, Liu LM, Zhou Y, Zhang CL, Gu PL, Wu LL
Antioxidants & redox signaling 2019 Jul 1;31(1):75-91
Antioxidants & redox signaling 2019 Jul 1;31(1):75-91
Circulating osteopontin per tumor volume as a prognostic biomarker for resectable intrahepatic cholangiocarcinoma.
Zhou KQ, Liu WF, Yang LX, Sun YF, Hu J, Chen FY, Zhou C, Zhang XY, Peng YF, Yu L, Zhou J, Fan J, Wang Z
Hepatobiliary surgery and nutrition 2019 Dec;8(6):582-596
Hepatobiliary surgery and nutrition 2019 Dec;8(6):582-596
Effect of Hydroxyapatite Nanorods on the Fate of Human Adipose-Derived Stem Cells Assessed In Situ at the Single Cell Level with a High-Throughput, Real-Time Microfluidic Chip.
Hao M, He J, Wang C, Wang C, Ma B, Zhang S, Duan J, Liu F, Zhang Y, Han L, Liu H, Sang Y
Small (Weinheim an der Bergstrasse, Germany) 2019 Dec;15(51):e1905001
Small (Weinheim an der Bergstrasse, Germany) 2019 Dec;15(51):e1905001
Efficient osteogenic differentiation of the dental pulp stem cells on β-glycerophosphate loaded polycaprolactone/polyethylene oxide blend nanofibers.
Hosseini FS, Enderami SE, Hadian A, Abazari MF, Ardeshirylajimi A, Saburi E, Soleimanifar F, Nazemisalman B
Journal of cellular physiology 2019 Aug;234(8):13951-13958
Journal of cellular physiology 2019 Aug;234(8):13951-13958
Quantitative proteomics of milk whey reveals breed and season specific variation in protein abundance in Holstein Friesian cow and Murrah buffalo.
Maity S, Ambatipudi K
Research in veterinary science 2019 Aug;125:244-252
Research in veterinary science 2019 Aug;125:244-252
Effect of microRNA-21 on hypoxia-inducible factor-1α in orthodontic tooth movement and human periodontal ligament cells under hypoxia.
Zhang X, Chen D, Zheng J, Deng L, Chen Z, Ling J, Wu L
Experimental and therapeutic medicine 2019 Apr;17(4):2830-2836
Experimental and therapeutic medicine 2019 Apr;17(4):2830-2836
Promoting osteogenic differentiation of human-induced pluripotent stem cells by releasing Wnt/β-catenin signaling activator from the nanofibers.
Hosseini FS, Soleimanifar F, Khojasteh A, Ardeshirylajimi A
Journal of cellular biochemistry 2019 Apr;120(4):6339-6346
Journal of cellular biochemistry 2019 Apr;120(4):6339-6346
New Application of Psoralen and Angelicin on Periodontitis With Anti-bacterial, Anti-inflammatory, and Osteogenesis Effects.
Li X, Yu C, Hu Y, Xia X, Liao Y, Zhang J, Chen H, Lu W, Zhou W, Song Z
Frontiers in cellular and infection microbiology 2018;8:178
Frontiers in cellular and infection microbiology 2018;8:178
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.
Jiang H, Gao X, Gong J, Yang Q, Lan R, Wang T, Liu J, Yin C, Wang S, Liu Z
Oxidative medicine and cellular longevity 2018;2018:1724648
Oxidative medicine and cellular longevity 2018;2018:1724648
Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.
Che C, Liu J, Yang J, Ma L, Bai N, Zhang Q
Clinical implant dentistry and related research 2018 Jun;20(3):384-392
Clinical implant dentistry and related research 2018 Jun;20(3):384-392
Hypoxia-Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis.
Song X, Yang C, Zhang H, Wang J, Sun X, Hu L, Liu Z, Wang D
The Annals of otology, rhinology, and laryngology 2018 Jun;127(6):357-366
The Annals of otology, rhinology, and laryngology 2018 Jun;127(6):357-366
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
Zhang JR, Lu QB, Feng WB, Wang HP, Tang ZH, Cheng H, Du Q, Wang YB, Li KX, Sun HJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:711-717
Negative pressure wound therapy promotes muscle-derived stem cell osteogenic differentiation through MAPK pathway.
Liu H, Zheng X, Chen L, Jian C, Hu X, Zhao Y, Li Z, Yu A
Journal of cellular and molecular medicine 2018 Jan;22(1):511-520
Journal of cellular and molecular medicine 2018 Jan;22(1):511-520
Teniposide regulates the phenotype switching of vascular smooth muscle cells in a miR-21-dependent manner.
Han H, Yang S, Liang Y, Zeng P, Liu L, Yang X, Duan Y, Han J, Chen Y
Biochemical and biophysical research communications 2018 Dec 2;506(4):1040-1046
Biochemical and biophysical research communications 2018 Dec 2;506(4):1040-1046
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.
Fan S, Gao X, Chen P, Li X
Life sciences 2018 Aug 15;207:205-211
Life sciences 2018 Aug 15;207:205-211
Osteopontin contributes to effective neutrophil recruitment, IL-1β production and apoptosis in Aspergillus fumigatus keratitis.
Zhao G, Hu M, Li C, Lee J, Yuan K, Zhu G, Che C
Immunology and cell biology 2018 Apr;96(4):401-412
Immunology and cell biology 2018 Apr;96(4):401-412
The prognostic value of osteopontin in limited-stage small cell lung cancer patients and its mechanism.
Liu F, Bai C, Guo Z
Oncotarget 2017 Sep 19;8(41):70084-70096
Oncotarget 2017 Sep 19;8(41):70084-70096
The protective effect of PFTα on alcohol-induced osteonecrosis of the femoral head.
Chen YX, Zhu DY, Yin JH, Yin WJ, Zhang YL, Ding H, Yu XW, Mei J, Gao YS, Zhang CQ
Oncotarget 2017 Nov 21;8(59):100691-100707
Oncotarget 2017 Nov 21;8(59):100691-100707
MgAl layered double hydroxide/chitosan porous scaffolds loaded with PFTα to promote bone regeneration.
Chen YX, Zhu R, Ke QF, Gao YS, Zhang CQ, Guo YP
Nanoscale 2017 May 25;9(20):6765-6776
Nanoscale 2017 May 25;9(20):6765-6776
Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines.
Januchowski R, Sterzyńska K, Zawierucha P, Ruciński M, Świerczewska M, Partyka M, Bednarek-Rajewska K, Brązert M, Nowicki M, Zabel M, Klejewski A
Oncotarget 2017 Jul 25;8(30):49944-49958
Oncotarget 2017 Jul 25;8(30):49944-49958
Transcriptome analysis in primary colorectal cancer tissues from patients with and without liver metastases using next-generation sequencing.
Wang S, Zhang C, Zhang Z, Qian W, Sun Y, Ji B, Zhang Y, Zhu C, Ji D, Wang Q, Sun Y
Cancer medicine 2017 Aug;6(8):1976-1987
Cancer medicine 2017 Aug;6(8):1976-1987
MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin.
Zhang ZW, Guo RW, Lv JL, Wang XM, Ye JS, Lu NH, Liang X, Yang LX
Biochemical and biophysical research communications 2017 Apr 29;486(2):414-422
Biochemical and biophysical research communications 2017 Apr 29;486(2):414-422
Interleukin-6 enhances cancer stemness and promotes metastasis of hepatocellular carcinoma via up-regulating osteopontin expression.
Wang CQ, Sun HT, Gao XM, Ren N, Sheng YY, Wang Z, Zheng Y, Wei JW, Zhang KL, Yu XX, Zhu Y, Luo Q, Yang LY, Dong QZ, Qin LX
American journal of cancer research 2016;6(9):1873-1889
American journal of cancer research 2016;6(9):1873-1889
Intrarenal macrophage infiltration induced by T cells is associated with podocyte injury in lupus nephritis patients.
Ma R, Jiang W, Li Z, Sun Y, Wei Z
Lupus 2016 Dec;25(14):1577-1586
Lupus 2016 Dec;25(14):1577-1586
Comparative investigation of human amniotic epithelial cells and mesenchymal stem cells for application in bone tissue engineering.
Si J, Dai J, Zhang J, Liu S, Gu J, Shi J, Shen SG, Guo L
Stem cells international 2015;2015:565732
Stem cells international 2015;2015:565732
The chemokine CXCL13 in lung cancers associated with environmental polycyclic aromatic hydrocarbons pollution.
Wang GZ, Cheng X, Zhou B, Wen ZS, Huang YC, Chen HB, Li GF, Huang ZL, Zhou YC, Feng L, Wei MM, Qu LW, Cao Y, Zhou GB
eLife 2015 Nov 13;4
eLife 2015 Nov 13;4
Serum anti-osteopontin autoantibody as a novel diagnostic and prognostic biomarker in patients with hepatocellular carcinoma.
Ying X, Zhao Y, Wang JL, Zhou X, Zhao J, He CC, Guo XJ, Jin GH, Wang LJ, Zhu Q, Han SX
Oncology reports 2014 Oct;32(4):1550-6
Oncology reports 2014 Oct;32(4):1550-6
Protective effects of epigallocatechin gallate (EGCG) on streptozotocin-induced diabetic nephropathy in mice.
Yoon SP, Maeng YH, Hong R, Lee BR, Kim CG, Kim HL, Chung JH, Shin BC
Acta histochemica 2014 Oct;116(8):1210-5
Acta histochemica 2014 Oct;116(8):1210-5
Characterization of a micro-roughened TiO2/ZrO2 coating: mechanical properties and HBMSC responses in vitro.
Si J, Zhang J, Liu S, Zhang W, Yu D, Wang X, Guo L, Shen SG
Acta biochimica et biophysica Sinica 2014 Jul;46(7):572-81
Acta biochimica et biophysica Sinica 2014 Jul;46(7):572-81
Osteogenic differentiation of human amniotic epithelial cells and its application in alveolar defect restoration.
Jiawen S, Jianjun Z, Jiewen D, Dedong Y, Hongbo Y, Jun S, Xudong W, Shen SG, Lihe G
Stem cells translational medicine 2014 Dec;3(12):1504-13
Stem cells translational medicine 2014 Dec;3(12):1504-13
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 22952-1-AP( OPN, SPP1 Antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human stomach cancer using 22952-1-AP(OPN, SPP1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Osteopontin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Osteopontin. This antibody recognizes human, mouse antigen. The Osteopontin antibody has been validated for the following applications: ELISA, IHC, WB analysis.
