Antibody data
- Antibody Data
- Antigen structure
- References [28]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 10458-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10458-1-AP, RRID:AB_2250289
- Product name
- Myelin basic protein antibody
- Antibody type
- Polyclonal
- Description
- Myelin basic protein antibody (Cat. #10458-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references E3 ubiquitin ligase Triad1 promotes neuronal apoptosis by regulating the p53-caspase3 pathway after spinal cord injury.
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice.
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
Evaluation of cytokines and structural proteins to analyze the pathology of febrile central nervous system disease.
Intranasal administration of DHED protects against exhaustive exercise-induced brain injury in rats.
An in vivo implementation of the MEX MRI for myelin fraction of mice brain.
Caffeic Acid Phenethyl Ester Protects against Experimental Autoimmune Encephalomyelitis by Regulating T Cell Activities.
Acupuncture Improves White Matter Perfusion and Integrity in Rat Model of Vascular Dementia: An MRI-Based Imaging Study.
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
The combined treatment of NAD+ and atorvastatin ameliorates the development of experimental autoimmune encephalomyelitis in C57BL/6 mice.
Subarachnoid transplantation of human umbilical cord mesenchymal stem cell in rodent model with subacute incomplete spinal cord injury: Preclinical safety and efficacy study.
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Sevoflurane anesthesia during pregnancy in mice induces cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis.
Arsenic trioxide ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice by inducing CD4+ T cell apoptosis.
Triclosan induces zebrafish neurotoxicity by abnormal expression of miR-219 targeting oligodendrocyte differentiation of central nervous system.
Amelioration of clinical course and demyelination in the cuprizone mouse model in relation to ketogenic diet.
Chronic Sleep Restriction in Developing Male Mice Results in Long Lasting Behavior Impairments.
Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinct from Astrocytopathy Induced by AQP4-IgG.
Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Sigma-1 receptor activation alleviates blood-brain barrier dysfunction in vascular dementia mice.
Structural and visual functional deficits in a rat model of neuromyelitis optica spectrum disorders related optic neuritis.
ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons.
Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia.
Treatment with NAD(+) inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice.
Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response.
Wu C, Zhang H, Hong H, Chen C, Chen J, Zhang J, Xue P, Jiang J, Cui Z
Somatosensory & motor research 2022 Mar;39(1):21-28
Somatosensory & motor research 2022 Mar;39(1):21-28
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
Yu W, Jin H, Sun W, Nan D, Deng J, Jia J, Yu Z, Huang Y
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice.
Ding J, Huang J, Xia B, Hu S, Fan H, Dai J, Li Z, Wang J, Le C, Qiu P, Wang Y
Toxicology letters 2021 Nov 1;352:34-45
Toxicology letters 2021 Nov 1;352:34-45
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Wu X, Sheng H, Wang L, Xia P, Wang Y, Yu L, Lv W, Hu J
Aging 2021 Mar 26;13(7):10034-10057
Aging 2021 Mar 26;13(7):10034-10057
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
Zhang S, Liu B, Zhu H, Jin H, Gong Z, Qiu H, Xu M, Chen M, Nan K, Wu W
Neuroscience 2021 Jun 15;465:71-84
Neuroscience 2021 Jun 15;465:71-84
Evaluation of cytokines and structural proteins to analyze the pathology of febrile central nervous system disease.
Ikeda T, Tani N, Watanabe M, Hirokawa T, Ikeda K, Morioka F, Ishikawa T
Legal medicine (Tokyo, Japan) 2021 Jul;51:101864
Legal medicine (Tokyo, Japan) 2021 Jul;51:101864
Intranasal administration of DHED protects against exhaustive exercise-induced brain injury in rats.
Peng G, Zheng H, Wu C, Wu C, Ma X, Xiong J, Hou J, Zhang L, Yang L, Pan H
Brain research 2021 Dec 1;1772:147665
Brain research 2021 Dec 1;1772:147665
An in vivo implementation of the MEX MRI for myelin fraction of mice brain.
Wilczynski E, Sasson E, Eliav U, Navon G, Nevo U
Magma (New York, N.Y.) 2021 Aug 6;
Magma (New York, N.Y.) 2021 Aug 6;
Caffeic Acid Phenethyl Ester Protects against Experimental Autoimmune Encephalomyelitis by Regulating T Cell Activities.
Zhou Y, Wang J, Chang Y, Li R, Sun X, Peng L, Zheng W, Qiu W
Oxidative medicine and cellular longevity 2020;2020:7274342
Oxidative medicine and cellular longevity 2020;2020:7274342
Acupuncture Improves White Matter Perfusion and Integrity in Rat Model of Vascular Dementia: An MRI-Based Imaging Study.
Ma SM, Wang L, Su XT, Yang NN, Huang J, Lin LL, Shao JK, Yang JW, Liu CZ
Frontiers in aging neuroscience 2020;12:582904
Frontiers in aging neuroscience 2020;12:582904
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Yu Y, Wu DM, Li J, Deng SH, Liu T, Zhang T, He M, Zhao YY, Xu Y
Frontiers in immunology 2020;11:593368
Frontiers in immunology 2020;11:593368
The combined treatment of NAD+ and atorvastatin ameliorates the development of experimental autoimmune encephalomyelitis in C57BL/6 mice.
Sun H, Wang J, Guo L, Wang Y, Zhang J, Wang J, Quan M, Li B
Journal of neuroimmunology 2020 Oct 24;350:577429
Journal of neuroimmunology 2020 Oct 24;350:577429
Subarachnoid transplantation of human umbilical cord mesenchymal stem cell in rodent model with subacute incomplete spinal cord injury: Preclinical safety and efficacy study.
Yang Y, Cao TT, Tian ZM, Gao H, Wen HQ, Pang M, He WJ, Wang NX, Chen YY, Wang Y, Li H, Lin JW, Kang Z, Li MM, Liu B, Rong LM
Experimental cell research 2020 Oct 15;395(2):112184
Experimental cell research 2020 Oct 15;395(2):112184
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Chen M, Yang LL, Hu ZW, Qin C, Zhou LQ, Duan YL, Bosco DB, Wu LJ, Zhan KB, Xu SB, Tian DS
Journal of neuroinflammation 2020 Nov 6;17(1):333
Journal of neuroinflammation 2020 Nov 6;17(1):333
Sevoflurane anesthesia during pregnancy in mice induces cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis.
Zuo Y, Li B, Xie J, Ma Z, Thirupathi A, Yu P, Gao G, Zhou J, Zhou C, Xu H, Chang Y, Shi Z
Neurochemistry international 2020 May;135:104693
Neurochemistry international 2020 May;135:104693
Arsenic trioxide ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice by inducing CD4+ T cell apoptosis.
An K, Xue MJ, Zhong JY, Yu SN, Lan TS, Qi ZQ, Xia JJ
Journal of neuroinflammation 2020 May 6;17(1):147
Journal of neuroinflammation 2020 May 6;17(1):147
Triclosan induces zebrafish neurotoxicity by abnormal expression of miR-219 targeting oligodendrocyte differentiation of central nervous system.
Ling Y, Sun L, Wang D, Jiang J, Sun W, Ai W, Wang X, Wang H
Archives of toxicology 2020 Mar;94(3):857-871
Archives of toxicology 2020 Mar;94(3):857-871
Amelioration of clinical course and demyelination in the cuprizone mouse model in relation to ketogenic diet.
Zhang N, Liu C, Zhang R, Jin L, Yin X, Zheng X, Siebert HC, Li Y, Wang Z, Loers G, Petridis AK
Food & function 2020 Jun 24;11(6):5647-5663
Food & function 2020 Jun 24;11(6):5647-5663
Chronic Sleep Restriction in Developing Male Mice Results in Long Lasting Behavior Impairments.
Saré RM, Song A, Levine M, Lemons A, Loutaev I, Sheeler C, Hildreth C, Mfon A, Cooke S, Smith CB
Frontiers in behavioral neuroscience 2019;13:90
Frontiers in behavioral neuroscience 2019;13:90
Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinct from Astrocytopathy Induced by AQP4-IgG.
Fang L, Kang X, Wang Z, Wang S, Wang J, Zhou Y, Chen C, Sun X, Yan Y, Kermode AG, Peng L, Qiu W
Neuroscience bulletin 2019 Oct;35(5):853-866
Neuroscience bulletin 2019 Oct;35(5):853-866
Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.
Zhou C, Wang M, Yang J, Xiong H, Wang Y, Tang J
Cell communication and signaling : CCS 2019 Aug 22;17(1):105
Cell communication and signaling : CCS 2019 Aug 22;17(1):105
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Wang L, Pei S, Han L, Guo B, Li Y, Duan R, Yao Y, Xue B, Chen X, Jia Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Sigma-1 receptor activation alleviates blood-brain barrier dysfunction in vascular dementia mice.
Liu DY, Chi TY, Ji XF, Liu P, Qi XX, Zhu L, Wang ZQ, Li L, Chen L, Zou LB
Experimental neurology 2018 Oct;308:90-99
Experimental neurology 2018 Oct;308:90-99
Structural and visual functional deficits in a rat model of neuromyelitis optica spectrum disorders related optic neuritis.
Zhang Y, Bao Y, Qiu W, Peng L, Fang L, Xu Y, Yang H
Experimental eye research 2018 Oct;175:124-132
Experimental eye research 2018 Oct;175:124-132
ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons.
Szewczyk LM, Brozko N, Nagalski A, Röckle I, Werneburg S, Hildebrandt H, Wisniewska MB, Kuznicki J
Glia 2017 Jan;65(1):34-49
Glia 2017 Jan;65(1):34-49
Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia.
Zhu Y, Zhang Q, Zhang W, Li N, Dai Y, Tu J, Yang F, Brann DW, Wang R
Scientific reports 2017 Feb 16;7:42660
Scientific reports 2017 Feb 16;7:42660
Treatment with NAD(+) inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice.
Wang J, Zhao C, Kong P, Sun H, Sun Z, Bian G, Sun Y, Guo L
International immunopharmacology 2016 Oct;39:287-294
International immunopharmacology 2016 Oct;39:287-294
Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response.
Wang J, Zhao C, Kong P, Bian G, Sun Z, Sun Y, Guo L, Li B
Journal of neuroimmunology 2016 Oct 15;299:45-52
Journal of neuroimmunology 2016 Oct 15;299:45-52
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The Myelin basic protein antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Myelin basic protein. This antibody recognizes human,mouse,rat antigen. The Myelin basic protein antibody has been validated for the following applications: ELISA, WB analysis.