BS6660

antibody from Bioworld Technology, Inc
Targeting: MBP
Provider product page for BS6660
Western blot
Immunohistochemistry

Antibody data

Product number
BS6660 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MBP polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human MBP.
Description
Myelin basic protein (MBP) is the major extrinsic membrane protein of central nervous system myelin. MBP phosphorylation at Threonine 125 is a complex regulatory process that modulates the contribution of MBP to the stability of the myelin sheath. Mitogen-activated protein kinases modulate MBP phosphorylation during myelinogenesis and in the demyelinating disease multiple sclerosis. MBP phosphorylation is regulated by high-frequency stimulation but not low-frequency stimulation of the alveus, the myelinated output fibers of the hippocampus. It is proposed that during periods of increased neuronal activity, calcium activates axonal nitric oxide synthase, which generates the intercellular messengers nitric oxide and superoxide and regulates the phosphorylation state of MBP by MAPK.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MBP protein structure - BS6660 shown in red.