Tissue expression
Cell line expression
Protein structure
CD163
CD163 moleculeM130, MM130, SCARI1
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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Proteintech Group | 16646-1-AP | 35 references | Polyclonal |
WB
EL
ICC
IHC
FC
|
|
Novus Biologicals | NB110-40686 | 7 references | Monoclonal |
WB
EL
ICC
IHC
FC
|
|
GeneTex | GTX54458 | 1 references | Monoclonal |
WB
ICC
IP
IHC
BN
FA |
|
antibodies-online | ABIN741570 | 5 references | Polyclonal |
WB
ICC
IHC
FC |
|
Invitrogen Antibodies | MA5-11458 | 44 references | Monoclonal |
WB
IHC
OA
|
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