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- Antigen structure
- References [22]
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- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 13801-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13801-1-AP, RRID:AB_2186881
- Product name
- PAI-1 antibody
- Antibody type
- Polyclonal
- Description
- PAI-1 antibody (Cat. #13801-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Loss of TARBP2 Drives the Progression of Hepatocellular Carcinoma via miR-145-SERPINE1 Axis.
Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling.
Aberrant elevation of GDF8 impairs granulosa cell glucose metabolism via upregulating SERPINE1 expression in patients with PCOS.
Systemic sclerosis biomarkers detection in the secretome of TGFβ1-activated primary human lung fibroblasts.
ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer.
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
miR-18a Inhibits BMP4 and HIF-1α Normalizing Brain Arteriovenous Malformations.
A translational program that suppresses metabolism to shield the genome.
A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism.
Cross-Talk between Transforming Growth Factor-β and Periostin Can Be Targeted for Pulmonary Fibrosis.
Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway.
Transcriptome sequencing reveals fibrotic associated-genes involved in bovine mammary fibroblasts with Staphylococcus aureus.
Knockdown of TRIM27 expression suppresses the dysfunction of mesangial cells in lupus nephritis by FoxO1 pathway.
PAI-1 secreted from metastatic ovarian cancer cells triggers the tumor-promoting role of the mesothelium in a feedback loop to accelerate peritoneal dissemination.
Herba Artemisiae Capillaris Extract Prevents the Development of Streptozotocin-Induced Diabetic Nephropathy of Rat.
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Hypoxia induces TFE3 expression in head and neck squamous cell carcinoma.
Development of a Biomimetic Chondroitin Sulfate-modified Hydrogel to Enhance the Metastasis of Tumor Cells.
Inhibition of mTOR reduce Stat3 and PAI related angiogenesis in salivary gland adenoid cystic carcinoma.
Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis.
Global secretome characterization of A549 human alveolar epithelial carcinoma cells during Mycoplasma pneumoniae infection.
Tryptase promotes atherosclerotic plaque haemorrhage in ApoE-/- mice.
Li LM, Chen C, Ran RX, Huang JT, Sun HL, Zeng C, Zhang Z, Zhang W, Liu SM
Frontiers in oncology 2021;11:620912
Frontiers in oncology 2021;11:620912
Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling.
Xu X, Sun X, Wan X, Chen X, Jiang X
Toxicology letters 2021 Nov 1;352:61-69
Toxicology letters 2021 Nov 1;352:61-69
Aberrant elevation of GDF8 impairs granulosa cell glucose metabolism via upregulating SERPINE1 expression in patients with PCOS.
Bai L, Wang W, Xiang Y, Wang S, Wan S, Zhu Y
Molecular therapy. Nucleic acids 2021 Mar 5;23:294-309
Molecular therapy. Nucleic acids 2021 Mar 5;23:294-309
Systemic sclerosis biomarkers detection in the secretome of TGFβ1-activated primary human lung fibroblasts.
Kendall RT, Renaud L, Baatz JE, Malaab M, Nguyen XX, Feghali-Bostwick CA
Journal of proteomics 2021 Jun 30;242:104243
Journal of proteomics 2021 Jun 30;242:104243
ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer.
Taftaf R, Liu X, Singh S, Jia Y, Dashzeveg NK, Hoffmann AD, El-Shennawy L, Ramos EK, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Zhang Y, Davis AA, Reduzzi C, Cao Y, D'Amico P, Shen Y, Cristofanilli M, Muller WA, Varadan V, Liu H
Nature communications 2021 Aug 11;12(1):4867
Nature communications 2021 Aug 11;12(1):4867
Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
Mao Y, Li W, Hua B, Gu X, Pan W, Chen Q, Xu B, Wang Z, Lu C
BioMed research international 2020;2020:2406159
BioMed research international 2020;2020:2406159
miR-18a Inhibits BMP4 and HIF-1α Normalizing Brain Arteriovenous Malformations.
Marín-Ramos NI, Thein TZ, Ghaghada KB, Chen TC, Giannotta SL, Hofman FM
Circulation research 2020 Oct 9;127(9):e210-e231
Circulation research 2020 Oct 9;127(9):e210-e231
A translational program that suppresses metabolism to shield the genome.
Balukoff NC, Ho JJD, Theodoridis PR, Wang M, Bokros M, Llanio LM, Krieger JR, Schatz JH, Lee S
Nature communications 2020 Nov 13;11(1):5755
Nature communications 2020 Nov 13;11(1):5755
A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism.
Ho JJD, Balukoff NC, Theodoridis PR, Wang M, Krieger JR, Schatz JH, Lee S
Nature communications 2020 May 29;11(1):2677
Nature communications 2020 May 29;11(1):2677
Cross-Talk between Transforming Growth Factor-β and Periostin Can Be Targeted for Pulmonary Fibrosis.
Nanri Y, Nunomura S, Terasaki Y, Yoshihara T, Hirano Y, Yokosaki Y, Yamaguchi Y, Feghali-Bostwick C, Ajito K, Murakami S, Conway SJ, Izuhara K
American journal of respiratory cell and molecular biology 2020 Feb;62(2):204-216
American journal of respiratory cell and molecular biology 2020 Feb;62(2):204-216
Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway.
Chen ZQ, Sun XH, Li XJ, Xu ZC, Yang Y, Lin ZY, Xiao HM, Zhang M, Quan SJ, Huang HQ
Acta pharmacologica Sinica 2020 Dec;41(12):1587-1596
Acta pharmacologica Sinica 2020 Dec;41(12):1587-1596
Transcriptome sequencing reveals fibrotic associated-genes involved in bovine mammary fibroblasts with Staphylococcus aureus.
Miao Z, Ding Y, Zhao N, Chen X, Cheng H, Wang J, Liu Y, Wang F
The international journal of biochemistry & cell biology 2020 Apr;121:105696
The international journal of biochemistry & cell biology 2020 Apr;121:105696
Knockdown of TRIM27 expression suppresses the dysfunction of mesangial cells in lupus nephritis by FoxO1 pathway.
Liu J, Feng X, Tian Y, Wang K, Gao F, Yang L, Li H, Tian Y, Yang R, Zhao L, Miao X, Huang J, Liu Q, Zhang W, Li Y, Wang C, Duan H, Liu S
Journal of cellular physiology 2019 Jul;234(7):11555-11566
Journal of cellular physiology 2019 Jul;234(7):11555-11566
PAI-1 secreted from metastatic ovarian cancer cells triggers the tumor-promoting role of the mesothelium in a feedback loop to accelerate peritoneal dissemination.
Peng Y, Kajiyama H, Yuan H, Nakamura K, Yoshihara M, Yokoi A, Fujikake K, Yasui H, Yoshikawa N, Suzuki S, Senga T, Shibata K, Kikkawa F
Cancer letters 2019 Feb 1;442:181-192
Cancer letters 2019 Feb 1;442:181-192
Herba Artemisiae Capillaris Extract Prevents the Development of Streptozotocin-Induced Diabetic Nephropathy of Rat.
Geng J, Yu X, Liu C, Sun C, Guo M, Li Z, Jin Y, Zou Y, Yu J
Evidence-based complementary and alternative medicine : eCAM 2018;2018:5180165
Evidence-based complementary and alternative medicine : eCAM 2018;2018:5180165
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Sun D, Liu Y, Wang H, Deng F, Zhang Y, Zhao S, Ma X, Wu H, Sun G
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
Hypoxia induces TFE3 expression in head and neck squamous cell carcinoma.
Sun ZJ, Yu GT, Huang CF, Bu LL, Liu JF, Ma SR, Zhang WF, Liu B, Zhang L
Oncotarget 2016 Mar 8;7(10):11651-63
Oncotarget 2016 Mar 8;7(10):11651-63
Development of a Biomimetic Chondroitin Sulfate-modified Hydrogel to Enhance the Metastasis of Tumor Cells.
Liu Y, Wang S, Sun D, Liu Y, Liu Y, Wang Y, Liu C, Wu H, Lv Y, Ren Y, Guo X, Sun G, Ma X
Scientific reports 2016 Jul 19;6:29858
Scientific reports 2016 Jul 19;6:29858
Inhibition of mTOR reduce Stat3 and PAI related angiogenesis in salivary gland adenoid cystic carcinoma.
Yu GT, Bu LL, Zhao YY, Liu B, Zhang WF, Zhao YF, Zhang L, Sun ZJ
American journal of cancer research 2014;4(6):764-75
American journal of cancer research 2014;4(6):764-75
Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis.
Liu Z, Gao Y, Hao F, Lou X, Zhang X, Li Y, Wu D, Xiao T, Yang L, Li Q, Qiu X, Wang E
Molecular biology reports 2014 Nov;41(11):7507-23
Molecular biology reports 2014 Nov;41(11):7507-23
Global secretome characterization of A549 human alveolar epithelial carcinoma cells during Mycoplasma pneumoniae infection.
Li S, Li X, Wang Y, Yang J, Chen Z, Shan S
BMC microbiology 2014 Feb 7;14:27
BMC microbiology 2014 Feb 7;14:27
Tryptase promotes atherosclerotic plaque haemorrhage in ApoE-/- mice.
Zhi X, Xu C, Zhang H, Tian D, Li X, Ning Y, Yin L
PloS one 2013;8(4):e60960
PloS one 2013;8(4):e60960
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 13801-1-AP(SERPINE1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-SERPINE1 (IP:13801-1-AP, 3ug; Detection:13801-1-AP 1:300) with SH-SY5Y cells lysate 2000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 13801-1-AP(SERPINE1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PAI-1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PAI-1. This antibody recognizes human,mouse,rat antigen. The PAI-1 antibody has been validated for the following applications: ELISA, IHC, WB, IP analysis.
