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CAMK2A
Calcium/calmodulin dependent protein kinase II alphaCAMKA, CaMKIINalpha, CaMKIIα, KIAA0968
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018]
Top validated antibodies |
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| Novus Biologicals |  NB100-1983 |
9 references | Monoclonal |
WB
EL
ICC
IP
IHC
RA
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| GeneTex | GTX41976 |
2 references | Monoclonal |
WB
EL
ICC
IP
IHC
RA
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| Proteintech Group | 20666-1-AP |
8 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | MA1-047 |
80 references | Monoclonal |
WB
ICC
OA
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| antibodies-online | ABIN2484549 |
2 references | Monoclonal |
WB
EL
ICC
IP
IHC
RA
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