Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Flow cytometry [4]
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Validation data
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- Product number
- GTX74773 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX74773, RRID:AB_376459
- Product name
- CD8 antibody [LT8]
- Antibody type
- Monoclonal
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- LT8
- Storage
- Store at +4¢XC or at -20¢XC if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Submitted references The anti-tumor effect of intravesical administration of normal urothelial cells on bladder cancer.
Exploring the innate immunological response of an alternative nonhuman primate model of infectious disease; the common marmoset.
CD20+ B cell depletion alters T cell homing.
Changes in immune cell populations in the periphery and liver of GBV-B-infected and convalescent tamarins (Saguinus labiatus).
Extracellular matrix metalloproteinase inducer shows active perivascular cuffs in multiple sclerosis.
Delayed onset of graft-versus-host disease in immunodeficent human leucocyte antigen-DQ8 transgenic, murine major histocompatibility complex class II-deficient mice repopulated by human peripheral blood mononuclear cells.
Expression of herpes simplex virus 1-encoded microRNAs in human trigeminal ganglia and their relation to local T-cell infiltrates.
Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses.
TCR-independent killing of B cell malignancies by anti-third-party CTLs: the critical role of MHC-CD8 engagement.
Characterization of lethal inhalational infection with Francisella tularensis in the common marmoset (Callithrix jacchus).
An integral protein of the inner nuclear membrane localizes to the mitotic spindle in mammalian cells.
A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.
Safety, immunogenicity, and efficacy of the ML29 reassortant vaccine for Lassa fever in small non-human primates.
Flow cytometric analysis on cross-reactivity of human-specific CD monoclonal antibodies with splenocytes of Aotus nancymaae, a non-human primate model for biomedical research.
Multiple sclerosis: T-cell receptor expression in distinct brain regions.
CD8 alpha is expressed by human monocytes and enhances Fc gamma R-dependent responses.
HIV-1 Nef interacts with inositol trisphosphate receptor to activate calcium signaling in T cells.
High-dose leptin activates human leukocytes via receptor expression on monocytes.
Molecular biology and function of CD4 and CD8.
Huang CP, Chen CC, Shyr CR
Cytotherapy 2017 Oct;19(10):1233-1245
Cytotherapy 2017 Oct;19(10):1233-1245
Exploring the innate immunological response of an alternative nonhuman primate model of infectious disease; the common marmoset.
Nelson M, Loveday M
Journal of immunology research 2014;2014:913632
Journal of immunology research 2014;2014:913632
CD20+ B cell depletion alters T cell homing.
Kap YS, van Driel N, Laman JD, Tak PP, 't Hart BA
Journal of immunology (Baltimore, Md. : 1950) 2014 May 1;192(9):4242-53
Journal of immunology (Baltimore, Md. : 1950) 2014 May 1;192(9):4242-53
Changes in immune cell populations in the periphery and liver of GBV-B-infected and convalescent tamarins (Saguinus labiatus).
Hood SP, Mee ET, Perkins H, Bowen O, Dale JM, Almond NM, Karayiannis P, Bright H, Berry NJ, Rose NJ
Virus research 2014 Jan 22;179:93-101
Virus research 2014 Jan 22;179:93-101
Extracellular matrix metalloproteinase inducer shows active perivascular cuffs in multiple sclerosis.
Agrawal SM, Williamson J, Sharma R, Kebir H, Patel K, Prat A, Yong VW
Brain : a journal of neurology 2013 Jun;136(Pt 6):1760-77
Brain : a journal of neurology 2013 Jun;136(Pt 6):1760-77
Delayed onset of graft-versus-host disease in immunodeficent human leucocyte antigen-DQ8 transgenic, murine major histocompatibility complex class II-deficient mice repopulated by human peripheral blood mononuclear cells.
Büchner SM, Sliva K, Bonig H, Völker I, Waibler Z, Kirberg J, Schnierle BS
Clinical and experimental immunology 2013 Aug;173(2):355-64
Clinical and experimental immunology 2013 Aug;173(2):355-64
Expression of herpes simplex virus 1-encoded microRNAs in human trigeminal ganglia and their relation to local T-cell infiltrates.
Held K, Junker A, Dornmair K, Meinl E, Sinicina I, Brandt T, Theil D, Derfuss T
Journal of virology 2011 Oct;85(19):9680-5
Journal of virology 2011 Oct;85(19):9680-5
Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses.
Hovden AO, Karlsen M, Jonsson R, Aarstad HJ, Appel S
BMC immunology 2011 Jan 5;12:2
BMC immunology 2011 Jan 5;12:2
TCR-independent killing of B cell malignancies by anti-third-party CTLs: the critical role of MHC-CD8 engagement.
Lask A, Goichberg P, Cohen A, Goren-Arbel R, Milstein O, Aviner S, Feine I, Ophir E, Reich-Zeliger S, Hagin D, Klein T, Nagler A, Berrebi A, Reisner Y
Journal of immunology (Baltimore, Md. : 1950) 2011 Aug 15;187(4):2006-14
Journal of immunology (Baltimore, Md. : 1950) 2011 Aug 15;187(4):2006-14
Characterization of lethal inhalational infection with Francisella tularensis in the common marmoset (Callithrix jacchus).
Nelson M, Lever MS, Dean RE, Savage VL, Salguero FJ, Pearce PC, Stevens DJ, Simpson AJ
Journal of medical microbiology 2010 Sep;59(Pt 9):1107-13
Journal of medical microbiology 2010 Sep;59(Pt 9):1107-13
An integral protein of the inner nuclear membrane localizes to the mitotic spindle in mammalian cells.
Buch C, Lindberg R, Figueroa R, Gudise S, Onischenko E, Hallberg E
Journal of cell science 2009 Jun 15;122(Pt 12):2100-7
Journal of cell science 2009 Jun 15;122(Pt 12):2100-7
A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.
Kap YS, van Meurs M, van Driel N, Koopman G, Melief MJ, Brok HP, Laman JD, 't Hart BA
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 Dec;57(12):1159-67
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 Dec;57(12):1159-67
Safety, immunogenicity, and efficacy of the ML29 reassortant vaccine for Lassa fever in small non-human primates.
Lukashevich IS, Carrion R Jr, Salvato MS, Mansfield K, Brasky K, Zapata J, Cairo C, Goicochea M, Hoosien GE, Ticer A, Bryant J, Davis H, Hammamieh R, Mayda M, Jett M, Patterson J
Vaccine 2008 Sep 26;26(41):5246-54
Vaccine 2008 Sep 26;26(41):5246-54
Flow cytometric analysis on cross-reactivity of human-specific CD monoclonal antibodies with splenocytes of Aotus nancymaae, a non-human primate model for biomedical research.
Daubenberger CA, Spirig R, Patarroyo ME, Pluschke G
Veterinary immunology and immunopathology 2007 Sep 15;119(1-2):14-20
Veterinary immunology and immunopathology 2007 Sep 15;119(1-2):14-20
Multiple sclerosis: T-cell receptor expression in distinct brain regions.
Junker A, Ivanidze J, Malotka J, Eiglmeier I, Lassmann H, Wekerle H, Meinl E, Hohlfeld R, Dornmair K
Brain : a journal of neurology 2007 Nov;130(Pt 11):2789-99
Brain : a journal of neurology 2007 Nov;130(Pt 11):2789-99
CD8 alpha is expressed by human monocytes and enhances Fc gamma R-dependent responses.
Gibbings DJ, Marcet-Palacios M, Sekar Y, Ng MC, Befus AD
BMC immunology 2007 Aug 1;8:12
BMC immunology 2007 Aug 1;8:12
HIV-1 Nef interacts with inositol trisphosphate receptor to activate calcium signaling in T cells.
Manninen A, Saksela K
The Journal of experimental medicine 2002 Apr 15;195(8):1023-32
The Journal of experimental medicine 2002 Apr 15;195(8):1023-32
High-dose leptin activates human leukocytes via receptor expression on monocytes.
Zarkesh-Esfahani H, Pockley G, Metcalfe RA, Bidlingmaier M, Wu Z, Ajami A, Weetman AP, Strasburger CJ, Ross RJ
Journal of immunology (Baltimore, Md. : 1950) 2001 Oct 15;167(8):4593-9
Journal of immunology (Baltimore, Md. : 1950) 2001 Oct 15;167(8):4593-9
Molecular biology and function of CD4 and CD8.
Parnes JR
Advances in immunology 1989;44:265-311
Advances in immunology 1989;44:265-311
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Staining of human peripheral blood lymphocytes with Mouse anti-Human CD8 (GTX74773)
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Staining of human peripheral blood lymphocytes with Mouse anti Human CD8 (GTX74773) :APC
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Staining of human peripheral blood lymphocytes with Mouse anti Human CD8:FITC (GTX74775)
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Staining of human peripheral blood lymphocytes with Mouse anti Human CD8:RPE (GTX74777)