Tissue expression
Cell line expression
Protein structure
HDAC4
Histone deacetylase 4BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 17449-1-AP | 18 references | Polyclonal |
WB
EL
IP
IHC |
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GeneTex | GTX110231 | 3 references | Polyclonal |
WB
ICC
IP
IHC |
|
Invitrogen Antibodies | PA5-29103 | Polyclonal |
WB
ICC
IHC
ChIP
OA
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Novus Biologicals | NBP2-16793 | 1 references | Polyclonal |
WB
ICC
IP
IHC |
|
antibodies-online | ABIN2029608 | Polyclonal |
WB
ICC
IP
IHC |
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