IRAK1

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

interleukin 1 receptor associated kinase 1

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

X:q28 (154010506 - 154019902)

Ensembl ID

ENSG00000184216  (ver. 99.38)

Orthologs

Mouse Irak1: ENSMUSG00000031392

UniProt

P51617

neXtProt

NX_P51617

Human splice variants
Mouse splice variants