Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- PAB0279 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB0279, RRID:AB_1019038
- Product name
- TRAF6 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of TRAF6.
- Antigen sequence
DAKPELLAFQRPTIPRNPK
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Altered expression of microRNA miR-146a correlates with the development of chronic renal inflammation.
TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains.
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies.
Ichii O, Otsuka S, Sasaki N, Namiki Y, Hashimoto Y, Kon Y
Kidney international 2012 Feb;81(3):280-92
Kidney international 2012 Feb;81(3):280-92
TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains.
Zucchelli S, Codrich M, Marcuzzi F, Pinto M, Vilotti S, Biagioli M, Ferrer I, Gustincich S
Human molecular genetics 2010 Oct 1;19(19):3759-70
Human molecular genetics 2010 Oct 1;19(19):3759-70
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies.
Zapata JM, Krajewska M, Krajewski S, Kitada S, Welsh K, Monks A, McCloskey N, Gordon J, Kipps TJ, Gascoyne RD, Shabaik A, Reed JC
Journal of immunology (Baltimore, Md. : 1950) 2000 Nov 1;165(9):5084-96
Journal of immunology (Baltimore, Md. : 1950) 2000 Nov 1;165(9):5084-96
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of TRAF6 in normal human tissues. Using TRAF6 polyclonal antibody (Cat # PAB0279) at 1 : 2000. TRAF6 is observed at ~66 KDa. Additional bands of lower molecular weight were seen in some cases, and may represent TRAF6 degradation fragments.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin- embedded tissue sections stained for TRAF6 using TRAF6 polyclonal antibody (Cat # PAB0279) at 1 : 2000. Hematoxylin-eosin counterstain. A, mouse spleen. B, mouse thymus.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin- embedded tissue sections stained for TRAF6 using TRAF6 polyclonal antibody (Cat # PAB0279) at 1:2000.Hematoxylin-eosin counterstain.A, mouse lymph node.B, mouse bone marrow.
- Validation comment
- Immunohistochemistry