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Cell line expression
Protein structure
CRADD
CASP2 and RIPK1 domain containing adaptor with death domainRAIDD
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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| Proteintech Group |  10401-1-AP |
4 references | Polyclonal |
WB
EL
IP
IHC
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| GeneTex | GTX61554 |
Monoclonal |
WB
ICC
IP
IHC
FC
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| Novus Biologicals | H00008738-M01 |
1 references | Monoclonal |
WB
EL
ICC
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| Invitrogen Antibodies | PA5-80501 |
Polyclonal |
WB
ICC
IHC
OA
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| Biorbyt | orb548417 |
Monoclonal |
WB
ICC
IP
IHC
FC
|
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