AF3098

antibody from R&D Systems

Targeting: RTN4 ASY, KIAA0886, NOGO, NSP-CL

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

AF3098

Provider

R&D Systems

Product name

Rat Nogo-A aa 2-172 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects rat Nogo-A in direct ELISAs and Western blots.

Reactivity

Rat

Host

Goat

Conjugate

Unconjugated

Antigen sequence

Q9JK11


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Indomethacin protects rats from neuronal damage induced by traumatic brain injury and suppresses hippocampal IL-1β release through the inhibition of Nogo-A expression.

Chao PK, Lu KT, Jhu JY, Wo YY, Huang TC, Ro LS, Yang YL
Journal of neuroinflammation 2012 Jun 7;9:121

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Oligodendrocyte-myelin glycoprotein and Nogo negatively regulate activity-dependent synaptic plasticity.

Raiker SJ, Lee H, Baldwin KT, Duan Y, Shrager P, Giger RJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Sep 15;30(37):12432-45

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Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition.

Robak LA, Venkatesh K, Lee H, Raiker SJ, Duan Y, Lee-Osbourne J, Hofer T, Mage RG, Rader C, Giger RJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 May 6;29(18):5768-83