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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB3678 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3678, RRID:AB_1578527
- Product name
- PDGFA polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PDGFA.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Phosphorylation of the carboxyl-terminal transactivation domain of c-Fos by extracellular signal-regulated kinase mediates the transcriptional activation of AP-1 and cellular transformation induced by platelet-derived growth factor.
Kinetics control preferential heterodimer formation of platelet-derived growth factor from unfolded A- and B-chains.
Platelet-derived growth factor induces the beta-gamma-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway.
Monje P, Marinissen MJ, Gutkind JS
Molecular and cellular biology 2003 Oct;23(19):7030-43
Molecular and cellular biology 2003 Oct;23(19):7030-43
Kinetics control preferential heterodimer formation of platelet-derived growth factor from unfolded A- and B-chains.
Müller C, Richter S, Rinas U
The Journal of biological chemistry 2003 May 16;278(20):18330-5
The Journal of biological chemistry 2003 May 16;278(20):18330-5
Platelet-derived growth factor induces the beta-gamma-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway.
Gianni D, Zambrano N, Bimonte M, Minopoli G, Mercken L, Talamo F, Scaloni A, Russo T
The Journal of biological chemistry 2003 Mar 14;278(11):9290-7
The Journal of biological chemistry 2003 Mar 14;278(11):9290-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The PDGFA polyclonal antibody (Cat # PAB3678) is used in Western blot to detect PDGFA in HL-60 cell lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human brain tissue reacted with PDGFA polyclonal antibody (Cat # PAB3678) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
