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MYD88
MYD88 innate immune signal transduction adaptorThis gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-16231 |
2 references | Monoclonal |
WB
ICC
FC
OA
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| OriGene | TA502117 |
1 references | Monoclonal |
WB
ICC
IHC
FC
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| antibodies-online | ABIN446974 |
2 references | Polyclonal |
WB
ICC
IP
IHC
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| R&D Systems | AF3109 |
5 references | Polyclonal |
WB
ICC
FC
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| Everest Biotech | EB06667 |
Polyclonal |
WB
EL
ICC
IHC
FC
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