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Protein structure
DKK1
Dickkopf WNT signaling pathway inhibitor 1DKK-1, SK
This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017]
Top validated antibodies |
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| Novus Biologicals |  H00022943-M11 |
10 references | Monoclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | MA5-32229 |
1 references | Monoclonal |
WB
ICC
IHC
FC
OA
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| Proteintech Group | 21112-1-AP |
21 references | Polyclonal |
WB
EL
ICC
IHC
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| Abnova Corporation | H00022943-M11 |
5 references | Monoclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN524880 |
6 references | Monoclonal |
WB
EL
IP
IHC
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