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ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [18]
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- Validations
- Western blot [3]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN258397 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Dynamin 1-Like (DNM1L) (AA 500-600), (Internal Region) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Epitope
- Internal Region, AA 500-600
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
Maternal L-Carnitine Supplementation Improves Brain Health in Offspring from Cigarette Smoke Exposed Mothers.
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Skeletal muscle autophagy and mitophagy in endurance-trained runners before and after a high-fat meal.
CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation.
Moderate traumatic brain injury is linked to acute behaviour deficits and long term mitochondrial alterations.
Unique fractal evaluation and therapeutic implications of mitochondrial morphology in malignant mesothelioma.
Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish.
CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling.
Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting.
AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons.
SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage.
Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: relevance to lung cancer.
Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease.
High fat diet induced developmental defects in the mouse: oocyte meiotic aneuploidy and fetal growth retardation/brain defects.
High-mobility group box 1 is essential for mitochondrial quality control.
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
Role of Drp1, a key mitochondrial fission protein, in neuropathic pain.
Kandimalla R, Manczak M, Yin X, Wang R, Reddy PH
Human molecular genetics 2018 Jan 1;27(1):30-40
Human molecular genetics 2018 Jan 1;27(1):30-40
Maternal L-Carnitine Supplementation Improves Brain Health in Offspring from Cigarette Smoke Exposed Mothers.
Chan YL, Saad S, Al-Odat I, Oliver BG, Pollock C, Jones NM, Chen H
Frontiers in molecular neuroscience 2017;10:33
Frontiers in molecular neuroscience 2017;10:33
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, Hu L, Tian S, Wu M, Hui L, Zhang H, Gao P
The EMBO journal 2017 May 15;36(10):1330-1347
The EMBO journal 2017 May 15;36(10):1330-1347
Skeletal muscle autophagy and mitophagy in endurance-trained runners before and after a high-fat meal.
Tarpey MD, Davy KP, McMillan RP, Bowser SM, Halliday TM, Boutagy NE, Davy BM, Frisard MI, Hulver MW
Molecular metabolism 2017 Dec;6(12):1597-1609
Molecular metabolism 2017 Dec;6(12):1597-1609
CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation.
Xu S, Wang P, Zhang H, Gong G, Gutierrez Cortes N, Zhu W, Yoon Y, Tian R, Wang W
Nature communications 2016 Oct 14;7:13189
Nature communications 2016 Oct 14;7:13189
Moderate traumatic brain injury is linked to acute behaviour deficits and long term mitochondrial alterations.
Chen H, Chan YL, Nguyen LT, Mao Y, de Rosa A, Beh IT, Chee C, Oliver B, Herok G, Saad S, Gorrie C
Clinical and experimental pharmacology & physiology 2016 Nov;43(11):1107-1114
Clinical and experimental pharmacology & physiology 2016 Nov;43(11):1107-1114
Unique fractal evaluation and therapeutic implications of mitochondrial morphology in malignant mesothelioma.
Lennon FE, Cianci GC, Kanteti R, Riehm JJ, Arif Q, Poroyko VA, Lupovitch E, Vigneswaran W, Husain A, Chen P, Liao JK, Sattler M, Kindler HL, Salgia R
Scientific reports 2016 Apr 15;6:24578
Scientific reports 2016 Apr 15;6:24578
Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish.
Zhang M, Sun T, Jian C, Lei L, Han P, Lv Q, Yang R, Zhou X, Xu J, Hu Y, Men Y, Huang Y, Zhang C, Zhu X, Wang X, Cheng H, Xiong JW
PloS one 2015;10(7):e0132567
PloS one 2015;10(7):e0132567
CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling.
Palubinsky AM, Stankowski JN, Kale AC, Codreanu SG, Singer RJ, Liebler DC, Stanwood GD, McLaughlin B
Antioxidants & redox signaling 2015 Aug 20;23(6):535-49
Antioxidants & redox signaling 2015 Aug 20;23(6):535-49
Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting.
Su YC, Chiu HW, Hung JC, Hong JR
Apoptosis : an international journal on programmed cell death 2014 Oct;19(10):1457-70
Apoptosis : an international journal on programmed cell death 2014 Oct;19(10):1457-70
AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons.
Amadoro G, Corsetti V, Florenzano F, Atlante A, Ciotti MT, Mongiardi MP, Bussani R, Nicolin V, Nori SL, Campanella M, Calissano P
Neurobiology of disease 2014 Feb;62:489-507
Neurobiology of disease 2014 Feb;62:489-507
SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage.
Tseng AH, Shieh SS, Wang DL
Free radical biology & medicine 2013 Oct;63:222-34
Free radical biology & medicine 2013 Oct;63:222-34
Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: relevance to lung cancer.
Kawada I, Hasina R, Lennon FE, Bindokas VP, Usatyuk P, Tan YH, Krishnaswamy S, Arif Q, Carey G, Hseu RD, Robinson M, Tretiakova M, Brand TM, Iida M, Ferguson MK, Wheeler DL, Husain AN, Natarajan V, Vokes EE, Singleton PA, Salgia R
Cancer biology & therapy 2013 Jul;14(7):679-91
Cancer biology & therapy 2013 Jul;14(7):679-91
Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease.
Bajpai P, Sangar MC, Singh S, Tang W, Bansal S, Chowdhury G, Cheng Q, Fang JK, Martin MV, Guengerich FP, Avadhani NG
The Journal of biological chemistry 2013 Feb 8;288(6):4436-51
The Journal of biological chemistry 2013 Feb 8;288(6):4436-51
High fat diet induced developmental defects in the mouse: oocyte meiotic aneuploidy and fetal growth retardation/brain defects.
Luzzo KM, Wang Q, Purcell SH, Chi M, Jimenez PT, Grindler N, Schedl T, Moley KH
PloS one 2012;7(11):e49217
PloS one 2012;7(11):e49217
High-mobility group box 1 is essential for mitochondrial quality control.
Tang D, Kang R, Livesey KM, Kroemer G, Billiar TR, Van Houten B, Zeh HJ 3rd, Lotze MT
Cell metabolism 2011 Jun 8;13(6):701-11
Cell metabolism 2011 Jun 8;13(6):701-11
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
Manczak M, Calkins MJ, Reddy PH
Human molecular genetics 2011 Jul 1;20(13):2495-509
Human molecular genetics 2011 Jul 1;20(13):2495-509
Role of Drp1, a key mitochondrial fission protein, in neuropathic pain.
Ferrari LF, Chum A, Bogen O, Reichling DB, Levine JD
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Aug 3;31(31):11404-10
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Aug 3;31(31):11404-10
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Supportive validation
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Supportive validation
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