BS8531

antibody from Bioworld Technology, Inc
Targeting: CASP14 MGC119078, MGC119079, MICE
Provider product page for BS8531
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8531 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Caspase 14 polyclonal antibody
Antibody type
Polyclonal
Antigen
Caspase14; Caspase-14; CASP-14; Caspase-14 subunit p10; CASP14
Description
Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p19 and p10 subunits by caspase-8. Caspase-14 may not play a role in apoptosis, but instead may regulate keratinocyte differentiation. Expression of caspase-14 may protect from psoriasis and irradiation damage. Caspase-14 may also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CASP14 protein structure - BS8531 shown in red.