Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 10724-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10724-1-AP, RRID:AB_2154209
- Product name
- NRAS antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NRAS antibody (Cat. #10724-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.
Polymeric nanoparticle mediated inhibition of miR-21 with enhanced miR-124 expression for combinatorial glioblastoma therapy.
Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6.
Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling.
Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System.
Immunohistochemical assessment of growth factor signaling molecules: MAPK, Akt, and STAT3 pathways in oral epithelial precursor lesions and squamous cell carcinoma.
Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
KRAS regulation by small non-coding RNAs and SNARE proteins.
Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression.
ANRIL lncRNA triggers efficient therapeutic efficacy by reprogramming the aberrant INK4-hub in melanoma.
Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.
Li XX, Xiong L, Wen Y, Zhang ZJ
Frontiers in genetics 2021;12:774400
Frontiers in genetics 2021;12:774400
Polymeric nanoparticle mediated inhibition of miR-21 with enhanced miR-124 expression for combinatorial glioblastoma therapy.
Liu Y, Zheng M, Jiao M, Yan C, Xu S, Du Q, Morsch M, Yin J, Shi B
Biomaterials 2021 Sep;276:121036
Biomaterials 2021 Sep;276:121036
Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6.
Qiu N, Abegg D, Guidi M, Gilmore K, Seeberger PH, Adibekian A
Cell chemical biology 2021 Jul 27;
Cell chemical biology 2021 Jul 27;
Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling.
Liu C, Lu H, Wang H, Loo A, Zhang X, Yang G, Kowal C, Delach S, Wang Y, Goldoni S, Hastings WD, Wong K, Gao H, Meyer MJ, Moody SE, LaMarche MJ, Engelman JA, Williams JA, Hammerman PS, Abrams TJ, Mohseni M, Caponigro G, Hao HX
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Jan 1;27(1):342-354
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Jan 1;27(1):342-354
Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System.
Röth S, Macartney TJ, Konopacka A, Chan KH, Zhou H, Queisser MA, Sapkota GP
Cell chemical biology 2020 Sep 17;27(9):1151-1163.e6
Cell chemical biology 2020 Sep 17;27(9):1151-1163.e6
Immunohistochemical assessment of growth factor signaling molecules: MAPK, Akt, and STAT3 pathways in oral epithelial precursor lesions and squamous cell carcinoma.
Tashiro K, Oikawa M, Miki Y, Takahashi T, Kumamoto H
Odontology 2020 Jan;108(1):91-101
Odontology 2020 Jan;108(1):91-101
Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
Zhao Y, Zhang Y, Vazirinejad Mehdiabad M, Zhou K, Chen Y, Li L, Guo J, Xu C
PloS one 2019;14(10):e0223232
PloS one 2019;14(10):e0223232
KRAS regulation by small non-coding RNAs and SNARE proteins.
Che Y, Siprashvili Z, Kovalski JR, Jiang T, Wozniak G, Elcavage L, Khavari PA
Nature communications 2019 Nov 11;10(1):5118
Nature communications 2019 Nov 11;10(1):5118
Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression.
Guo S, Yang P, Jiang X, Li X, Wang Y, Zhang X, Sun B, Zhang Y, Jia Y
Oncotarget 2017 Jan 3;8(1):644-657
Oncotarget 2017 Jan 3;8(1):644-657
ANRIL lncRNA triggers efficient therapeutic efficacy by reprogramming the aberrant INK4-hub in melanoma.
Xu S, Wang H, Pan H, Shi Y, Li T, Ge S, Jia R, Zhang H, Fan X
Cancer letters 2016 Oct 10;381(1):41-8
Cancer letters 2016 Oct 10;381(1):41-8
Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.
Liu W, Ning R, Chen RN, Huang XF, Dai QS, Hu JH, Wang YW, Wu LL, Xiong J, Hu G, Guo QL, Yang J, Wang H
Molecular carcinogenesis 2016 May;55(5):440-57
Molecular carcinogenesis 2016 May;55(5):440-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 10724-1-AP(NRAS antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NRAS antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NRAS. This antibody recognizes human,mouse,rat antigen. The NRAS antibody has been validated for the following applications: ELISA, WB, IF, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 10724-1-AP(NRAS antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 10724-1-AP(NRAS antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue