Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
RASGRF1
Ras protein specific guanine nucleotide releasing factor 1CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
Top validated antibodies |
|||||
| Proteintech Group |  12958-1-AP |
5 references | Polyclonal |
WB
EL
IP
|
|
| Novus Biologicals | 27320002 |
2 references | Polyclonal |
WB
EL
IHC
|
|
| Abnova Corporation | PAB2980 |
2 references | Polyclonal |
WB
IHC
|
|
| antibodies-online | ABIN2841679 |
1 references | Polyclonal |
WB
IHC
|
|
| Wuhan Fine Biotech Co., Ltd. | FNab07131 |
Polyclonal |
WB
EL
ICC
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider