BS6145

antibody from Bioworld Technology, Inc

Targeting: MAGED1 DLXIN-1, NRAGE

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: BS6145 - Provider product page
Provider: Bioworld Technology, Inc
Product name: MAGED1 polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human MAGED1.
Description: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds NGFR/p75NTR and antagonizes its association with NTRK1/TrkA, inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate TP53/p53 transcriptional activity and inhibit cell proliferation. Enhances TP53 phosphorylation and accumulation. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

MAGED1 protein structure - BS6145 shown in red.