BS8316

antibody from Bioworld Technology, Inc
Targeting: KIF1B CMT2, CMT2A, HMSNII, KIAA0591, KLP
Provider product page for BS8316
Western blot
Immunohistochemistry

Antibody data

Product number
BS8316 - Provider product page
Provider
Bioworld Technology, Inc
Product name
KIF1B polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human KIF1B.
Description
The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell . Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36.2. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype. The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
KIF1B protein structure - BS8316 shown in red.