Tissue expression
Cell line expression
Protein structure
FREM1
FRAS1 related extracellular matrix 1C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR
This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation. [provided by RefSeq, Apr 2011]
Top validated antibodies |
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Proteintech Group | 13086-1-AP | 2 references | Polyclonal |
WB
EL
ICC
IHC |
|
antibodies-online | ABIN783634 | 1 references | Polyclonal |
WB
EL
ICC
|
|
OriGene | AP31265PU-N | Polyclonal |
WB
EL
ICC
IHC |
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LSBio | LS-B5486 | Polyclonal |
WB
EL
ICC
IHC |
||
NovoPro Bioscience Inc. | 110720 | Polyclonal |
WB
EL
ICC
IHC |
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