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DUSP1
Dual specificity phosphatase 1CL100, HVH1, MKP-1, PTPN10
The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-32480 |
1 references | Monoclonal |
WB
IHC
FC
OA
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| Novus Biologicals | NBP2-67909 |
1 references | Monoclonal |
WB
IP
IHC
FC
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| Boster Biological Technology | M02276 |
Monoclonal |
WB
ICC
IP
IHC
FC
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| Biorbyt | orb547993 |
Monoclonal |
WB
ICC
IP
IHC
FC
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| antibodies-online | ABIN257653 |
1 references | Polyclonal |
WB
EL
IHC
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