Tissue expression
Cell line expression
Protein structure
SEPHS2
Selenophosphate synthetase 2SPS2, SPS2b
This gene encodes an enzyme that catalyzes the production of monoselenophosphate (MSP) from selenide and ATP. MSP is the selenium donor required for synthesis of selenocysteine (Sec), which is co-translationally incorporated into selenoproteins at in-frame UGA codons that normally signal translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is itself a selenoprotein containing a Sec residue at its active site, suggesting the existence of an autoregulatory mechanism. It is preferentially expressed in tissues implicated in the synthesis of selenoproteins and in sites of blood cell development. A pseudogene for this locus has been identified on chromosome 5. [provided by RefSeq, May 2017]
Top validated antibodies |
|||||
LSBio | LS-C133693 | Monoclonal |
WB
EL
IHC
|
||
antibodies-online | ABIN359369 | 4 references | Polyclonal |
WB
IHC |
|
Abnova Corporation | PAB2041 | 3 references | Polyclonal |
WB
IHC |
|
GeneTex | GTX103766 | Polyclonal |
WB
ICC
IHC
|
||
Novus Biologicals | H00022928-M02 | Monoclonal |
WB
EL
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider