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Cell line expression
Protein structure
FASLG
Fas ligandAPT1LG1, CD178, FasL, TNFSF6
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
Top validated antibodies |
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| R&D Systems |  AF126 |
4 references | Polyclonal |
WB
IHC
FC
BN
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| Novus Biologicals | AF126 |
4 references | Polyclonal |
WB
IHC
FC
BN
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| antibodies-online | ABIN2663100 |
Monoclonal |
WB
ICC
IP
IHC
FC
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| GeneTex | GTX31191 |
2 references | Polyclonal |
WB
EL
IHC
BN
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| Invitrogen Antibodies | 12-9919-42 |
13 references | Monoclonal |
FC
OA
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