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Learn13147-1-AP
antibody from Proteintech Group
Targeting: FOXM1
FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [43]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 13147-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13147-1-AP, RRID:AB_2106213
- Product name
- FOXM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FOXM1 antibody (Cat. #13147-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Comprehensive Analysis Uncovers Prognostic and Immunogenic Characteristics of Cellular Senescence for Lung Adenocarcinoma.
Development of a novel gene signature to predict prognosis and response to PD-1 blockade in clear cell renal cell carcinoma.
Paired-like homeodomain transcription factor 2 affects endometrial cell function and embryo implantation through the Wnt/β-catenin pathway.
The FOXM1/RNF26/p57 axis regulates the cell cycle to promote the aggressiveness of bladder cancer.
NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma.
LRPPRC regulates redox homeostasis via the circANKHD1/FOXM1 axis to enhance bladder urothelial carcinoma tumorigenesis.
FOXM1-activated SIRT4 inhibits NF-κB signaling and NLRP3 inflammasome to alleviate kidney injury and podocyte pyroptosis in diabetic nephropathy.
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Constitutive androstane receptor induced-hepatomegaly and liver regeneration is partially via yes-associated protein activation.
Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer.
Hsa_circ_0042823 accelerates cancer progression via miR-877-5p/FOXM1 axis in laryngeal squamous cell carcinoma.
Schisandrol B promotes liver enlargement via activation of PXR and YAP pathways in mice.
miR-877-5p Suppresses Gastric Cancer Cell Proliferation Through Targeting FOXM1.
Dexamethasone-Induced Liver Enlargement Is Related to PXR/YAP Activation and Lipid Accumulation but Not Hepatocyte Proliferation.
The differences of regulatory networks between papillary and anaplastic thyroid carcinoma: an integrative transcriptomics study.
FoxM1 promotes the migration of ovarian cancer cell through KRT5 and KRT7.
LncRNA MFI2-AS1 promotes HCC progression and metastasis by acting as a competing endogenous RNA of miR-134 to upregulate FOXM1 expression.
A Cdh1-FoxM1-Apc axis controls muscle development and regeneration.
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
MiR-346-5p promotes colorectal cancer cell proliferation in vitro and in vivo by targeting FBXL2 and activating the β-catenin signaling pathway.
UCHL3 promotes pancreatic cancer progression and chemo-resistance through FOXM1 stabilization.
Integrated Bioinformatics Analysis of Master Regulators in Anaplastic Thyroid Carcinoma.
Promotion of liver growth by CAR is accompanied by Akt pathway activation and FoxM1-Nedd4-mediated repression of PTEN.
circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1.
Suppression of Hepatocellular Carcinoma Progression through FOXM1 and EMT Inhibition via Hydroxygenkwanin-Induced miR-320a Expression.
Dynamically decreased miR-671-5p expression is associated with oncogenic transformation and radiochemoresistance in breast cancer.
PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development.
Expression and functional characterization of FOXM1 in non-small cell lung cancer.
3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.
Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation.
Minute Virus of Mice Inhibits Transcription of the Cyclin B1 Gene during Infection.
FOXM1 regulates glycolysis in hepatocellular carcinoma by transactivating glucose transporter 1 expression.
Association between FOXM1 and hedgehog signaling pathway in human cervical carcinoma by tissue microarray analysis.
Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.
miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer.
LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells.
POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation.
Silibinin-induced glioma cell apoptosis by PI3K-mediated but Akt-independent downregulation of FoxM1 expression.
Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.
Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer.
Effects of metformin on FOXM1 expression and on the biological behavior of acute leukemia cell lines.
Expression and significance of FOXM1 in human cervical cancer: a tissue micro-array study.
Lin W, Wang X, Wang Z, Shao F, Yang Y, Cao Z, Feng X, Gao Y, He J
Frontiers in cell and developmental biology 2021;9:780461
Frontiers in cell and developmental biology 2021;9:780461
Development of a novel gene signature to predict prognosis and response to PD-1 blockade in clear cell renal cell carcinoma.
Yin X, Wang Z, Wang J, Xu Y, Kong W, Zhang J
Oncoimmunology 2021;10(1):1933332
Oncoimmunology 2021;10(1):1933332
Paired-like homeodomain transcription factor 2 affects endometrial cell function and embryo implantation through the Wnt/β-catenin pathway.
Zhang H, Qi J, Guo J, Wang Y, Guan Y, Fan J, Sui L, Xu Y, Kong L, Yan B, Kong Y
Cell biology international 2021 Sep;45(9):1957-1965
Cell biology international 2021 Sep;45(9):1957-1965
The FOXM1/RNF26/p57 axis regulates the cell cycle to promote the aggressiveness of bladder cancer.
Yi L, Wang H, Li W, Ye K, Xiong W, Yu H, Jin X
Cell death & disease 2021 Oct 14;12(10):944
Cell death & disease 2021 Oct 14;12(10):944
NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma.
Su X, Yang Y, Yang Q, Pang B, Sun S, Wang Y, Qiao Q, Guo C, Liu H, Pang Q
BMC cancer 2021 Nov 5;21(1):1181
BMC cancer 2021 Nov 5;21(1):1181
LRPPRC regulates redox homeostasis via the circANKHD1/FOXM1 axis to enhance bladder urothelial carcinoma tumorigenesis.
Wei WS, Wang N, Deng MH, Dong P, Liu JY, Xiang Z, Li XD, Li ZY, Liu ZH, Peng YL, Li Z, Jiang LJ, Yao K, Ye YL, Lu WH, Zhang ZL, Zhou FJ, Liu ZW, Xie D, Yu CP
Redox biology 2021 Nov 27;48:102201
Redox biology 2021 Nov 27;48:102201
FOXM1-activated SIRT4 inhibits NF-κB signaling and NLRP3 inflammasome to alleviate kidney injury and podocyte pyroptosis in diabetic nephropathy.
Xu X, Zhang L, Hua F, Zhang C, Zhang C, Mi X, Qin N, Wang J, Zhu A, Qin Z, Zhou F
Experimental cell research 2021 Nov 15;408(2):112863
Experimental cell research 2021 Nov 15;408(2):112863
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Yang D, Ma Y, Zhao P, Ma J, He C
Experimental cell research 2021 Nov 15;408(2):112860
Experimental cell research 2021 Nov 15;408(2):112860
Constitutive androstane receptor induced-hepatomegaly and liver regeneration is partially via yes-associated protein activation.
Gao Y, Fan S, Li H, Jiang Y, Yao X, Zhu S, Yang X, Wang R, Tian J, Gonzalez FJ, Huang M, Bi H
Acta pharmaceutica Sinica. B 2021 Mar;11(3):727-737
Acta pharmaceutica Sinica. B 2021 Mar;11(3):727-737
Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer.
Wang RT, Miao RC, Zhang X, Yang GH, Mu YP, Zhang ZY, Qu K, Liu C
World journal of gastroenterology 2021 Feb 28;27(8):692-707
World journal of gastroenterology 2021 Feb 28;27(8):692-707
Hsa_circ_0042823 accelerates cancer progression via miR-877-5p/FOXM1 axis in laryngeal squamous cell carcinoma.
Wu T, Sun Y, Sun Z, Li S, Wang W, Yu B, Wang G
Annals of medicine 2021 Dec;53(1):960-970
Annals of medicine 2021 Dec;53(1):960-970
Schisandrol B promotes liver enlargement via activation of PXR and YAP pathways in mice.
Zhao YY, Yao XP, Jiao TY, Tian JN, Gao Y, Fan SC, Chen PP, Jiang YM, Zhou YY, Chen YX, Yang X, Huang M, Bi HC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153520
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153520
miR-877-5p Suppresses Gastric Cancer Cell Proliferation Through Targeting FOXM1.
Wu K, Yu Z, Tang Z, Wei W, Xie D, Xie Y, Xiao Q
OncoTargets and therapy 2020;13:4731-4742
OncoTargets and therapy 2020;13:4731-4742
Dexamethasone-Induced Liver Enlargement Is Related to PXR/YAP Activation and Lipid Accumulation but Not Hepatocyte Proliferation.
Jiao T, Yao X, Zhao Y, Zhou Y, Gao Y, Fan S, Chen P, Li X, Jiang Y, Yang X, Gonzalez FJ, Huang M, Bi H
Drug metabolism and disposition: the biological fate of chemicals 2020 Sep;48(9):830-839
Drug metabolism and disposition: the biological fate of chemicals 2020 Sep;48(9):830-839
The differences of regulatory networks between papillary and anaplastic thyroid carcinoma: an integrative transcriptomics study.
Pan Z, Li L, Qian Y, Ge X, Hu X, Zhang Y, Ge M, Huang P
Cancer biology & therapy 2020 Sep 1;21(9):853-862
Cancer biology & therapy 2020 Sep 1;21(9):853-862
FoxM1 promotes the migration of ovarian cancer cell through KRT5 and KRT7.
Zhang Z, Tu K, Liu F, Liang M, Yu K, Wang Y, Luo Y, Yang B, Qin Y, He D, Jiang G, Huang O, Zou Y
Gene 2020 Oct 5;757:144947
Gene 2020 Oct 5;757:144947
LncRNA MFI2-AS1 promotes HCC progression and metastasis by acting as a competing endogenous RNA of miR-134 to upregulate FOXM1 expression.
Wei Y, Wang Z, Zong Y, Deng D, Chen P, Lu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109890
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109890
A Cdh1-FoxM1-Apc axis controls muscle development and regeneration.
Chen Z, Li L, Xu S, Liu Z, Zhou C, Li Z, Liu Y, Wu W, Huang Y, Kuang M, Fan S, Li H, Li X, Song G, Wu WS, Chen J, Hou Y
Cell death & disease 2020 Mar 9;11(3):180
Cell death & disease 2020 Mar 9;11(3):180
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
Yu C, Cheng Z, Cui S, Mao X, Li B, Fu Y, Wang H, Jin H, Ye Q, Zhao X, Jiang L, Qin W
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
MiR-346-5p promotes colorectal cancer cell proliferation in vitro and in vivo by targeting FBXL2 and activating the β-catenin signaling pathway.
Pan S, Wu W, Ren F, Li L, Li Y, Li W, Wang A, Liu D, Dong Y
Life sciences 2020 Mar 1;244:117300
Life sciences 2020 Mar 1;244:117300
UCHL3 promotes pancreatic cancer progression and chemo-resistance through FOXM1 stabilization.
Song Z, Li J, Zhang L, Deng J, Fang Z, Xiang X, Xiong J
American journal of cancer research 2019;9(9):1970-1981
American journal of cancer research 2019;9(9):1970-1981
Integrated Bioinformatics Analysis of Master Regulators in Anaplastic Thyroid Carcinoma.
Pan Z, Li L, Fang Q, Qian Y, Zhang Y, Zhu J, Ge M, Huang P
BioMed research international 2019;2019:9734576
BioMed research international 2019;2019:9734576
Promotion of liver growth by CAR is accompanied by Akt pathway activation and FoxM1-Nedd4-mediated repression of PTEN.
Yarushkin AA, Mazin ME, Pustylnyak YA, Prokopyeva EA, Pustylnyak VO
Archives of biochemistry and biophysics 2019 Sep 15;672:108065
Archives of biochemistry and biophysics 2019 Sep 15;672:108065
circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1.
Cheng Z, Yu C, Cui S, Wang H, Jin H, Wang C, Li B, Qin M, Yang C, He J, Zuo Q, Wang S, Liu J, Ye W, Lv Y, Zhao F, Yao M, Jiang L, Qin W
Nature communications 2019 Jul 19;10(1):3200
Nature communications 2019 Jul 19;10(1):3200
Suppression of Hepatocellular Carcinoma Progression through FOXM1 and EMT Inhibition via Hydroxygenkwanin-Induced miR-320a Expression.
Chou LF, Chen CY, Yang WH, Chen CC, Chang JL, Leu YL, Liou MJ, Wang TH
Biomolecules 2019 Dec 21;10(1)
Biomolecules 2019 Dec 21;10(1)
Dynamically decreased miR-671-5p expression is associated with oncogenic transformation and radiochemoresistance in breast cancer.
Tan X, Li Z, Ren S, Rezaei K, Pan Q, Goldstein AT, Macri CJ, Cao D, Brem RF, Fu SW
Breast cancer research : BCR 2019 Aug 7;21(1):89
Breast cancer research : BCR 2019 Aug 7;21(1):89
PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development.
Zhang Y, Ye X, Chen L, Wu Q, Gao Y, Li Y
International journal of biological sciences 2018;14(5):531-541
International journal of biological sciences 2018;14(5):531-541
Expression and functional characterization of FOXM1 in non-small cell lung cancer.
Zhang Y, Qiao WB, Shan L
OncoTargets and therapy 2018;11:3385-3393
OncoTargets and therapy 2018;11:3385-3393
3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
Li W, Liu J, Fu W, Zheng X, Ren L, Liu S, Wang J, Ji T, Du G
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):132
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):132
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.
Macedo JC, Vaz S, Bakker B, Ribeiro R, Bakker PL, Escandell JM, Ferreira MG, Medema R, Foijer F, Logarinho E
Nature communications 2018 Jul 19;9(1):2834
Nature communications 2018 Jul 19;9(1):2834
Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation.
Izumi T, Imai J, Yamamoto J, Kawana Y, Endo A, Sugawara H, Kohata M, Asai Y, Takahashi K, Kodama S, Kaneko K, Gao J, Uno K, Sawada S, Kalinichenko VV, Ishigaki Y, Yamada T, Katagiri H
Nature communications 2018 Dec 13;9(1):5300
Nature communications 2018 Dec 13;9(1):5300
Minute Virus of Mice Inhibits Transcription of the Cyclin B1 Gene during Infection.
Fuller MS, Majumder K, Pintel DJ
Journal of virology 2017 Jul 15;91(14)
Journal of virology 2017 Jul 15;91(14)
FOXM1 regulates glycolysis in hepatocellular carcinoma by transactivating glucose transporter 1 expression.
Shang R, Pu M, Li Y, Wang D
Oncology reports 2017 Apr;37(4):2261-2269
Oncology reports 2017 Apr;37(4):2261-2269
Association between FOXM1 and hedgehog signaling pathway in human cervical carcinoma by tissue microarray analysis.
Chen H, Wang J, Yang H, Chen D, Li P
Oncology letters 2016 Oct;12(4):2664-2673
Oncology letters 2016 Oct;12(4):2664-2673
Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.
Xu Q, Fu R, Yin G, Liu X, Liu Y, Xiang M
Gene 2016 Mar 10;578(2):263-73
Gene 2016 Mar 10;578(2):263-73
miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer.
Tan X, Fu Y, Chen L, Lee W, Lai Y, Rezaei K, Tabbara S, Latham P, Teal CB, Man YG, Siegel RS, Brem RF, Fu SW
Oncotarget 2016 Jan 5;7(1):293-307
Oncotarget 2016 Jan 5;7(1):293-307
LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells.
Zhu P, Wang Y, Wu J, Huang G, Liu B, Ye B, Du Y, Gao G, Tian Y, He L, Fan Z
Nature communications 2016 Dec 1;7:13608
Nature communications 2016 Dec 1;7:13608
POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation.
Wang B, Ma A, Zhang L, Jin WL, Qian Y, Xu G, Qiu B, Yang Z, Liu Y, Xia Q, Liu Y
Nature communications 2015 Oct 29;6:8704
Nature communications 2015 Oct 29;6:8704
Silibinin-induced glioma cell apoptosis by PI3K-mediated but Akt-independent downregulation of FoxM1 expression.
Zhang M, Liu Y, Gao Y, Li S
European journal of pharmacology 2015 Oct 15;765:346-54
European journal of pharmacology 2015 Oct 15;765:346-54
Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.
Chen X, Meng Q, Wang C, Liu Q, Sun H, Huo X, Sun P, Yang X, Peng J, Liu K
Pharmaceutical research 2015 Feb;32(2):538-48
Pharmaceutical research 2015 Feb;32(2):538-48
Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer.
Wen N, Wang Y, Wen L, Zhao SH, Ai ZH, Wang Y, Wu B, Lu HX, Yang H, Liu WC, Li Y
Journal of translational medicine 2014 May 20;12:134
Journal of translational medicine 2014 May 20;12:134
Effects of metformin on FOXM1 expression and on the biological behavior of acute leukemia cell lines.
Zhang B, Liu LL, Mao X, Zhang DH
Molecular medicine reports 2014 Dec;10(6):3193-8
Molecular medicine reports 2014 Dec;10(6):3193-8
Expression and significance of FOXM1 in human cervical cancer: a tissue micro-array study.
Guan P, Chen H, Li HJ, Duan J, Chen JY
Clinical and investigative medicine. Medecine clinique et experimentale 2011 Feb 1;34(1):E1-7
Clinical and investigative medicine. Medecine clinique et experimentale 2011 Feb 1;34(1):E1-7
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse thymus tissue were subjected to SDS PAGE followed by western blot with 13147-1-AP(FOXM1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FOXM1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FOXM1. This antibody recognizes human,mouse,rat antigen. The FOXM1 antibody has been validated for the following applications: ELISA, WB, IP analysis.
