PNMA3

The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Description

PNMA family member 3

Tissue specificity

Tissue enhanced (epididymis)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

X (153056409 - 153060467)

Ensembl ID

ENSG00000183837  (ver. 103.38)

Orthologs

Mouse Pnma3: ENSMUSG00000046287

UniProt

Q9UL41

neXtProt

NX_Q9UL41

Human splice variants
Mouse splice variants

Protein structure