Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- NBP2-34602AF647 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal TfR (Transferrin R) Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa (Workshop IV). This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C in the dark.
Submitted references Iron, microbiota and colorectal cancer.
Ng O
Wiener medizinische Wochenschrift (1946) 2016 Oct;166(13-14):431-436
Wiener medizinische Wochenschrift (1946) 2016 Oct;166(13-14):431-436
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Supportive validation
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TfR (Transferrin R) Antibody (DF1513) [Alexa Fluor® 647] [NBP2-34602AF647] - A surface stain was performed on Jurkat cells with TfR (Transferrin R) Antibody (DF1513) NBP2-34602AF647 (blue) and a matched isotype control (orange).Cells were incubated in an antibody dilution of 2.5 mg/ml for 20 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 647.