APR04344G

antibody from Leading Biology

Targeting: TAPBP TAPA

Western blot (Recommended by provider)

Antibody Data

Product number

APR04344G

Provider

Leading Biology

Product name

TAPBP Antibody (N-term)

Antibody type

Polyclonal

Description

This gene encodes a transmembrane glycoprotein whichmediates interaction between newly assembled majorhistocompatibility complex (MHC) class I molecules and thetransporter associated with antigen processing (TAP), which isrequired for the transport of antigenic peptides across theendoplasmic reticulum membrane. This interaction is essential foroptimal peptide loading on the MHC class I molecule. Up to fourcomplexes of MHC class I and this protein may be bound to a singleTAP molecule. This protein contains a C-terminal double-lysinemotif (KKKAE) known to maintain membrane proteins in theendoplasmic reticulum. This gene lies within the majorhistocompatibility complex on chromosome 6. Alternative splicingresults in three transcript variants encoding different isoforms.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.