SNRPC

This gene encodes one of the specific protein components of the U1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. The encoded protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. The genome contains several pseudogenes of this functional gene. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Oct 2009]

Description

Small nuclear ribonucleoprotein polypeptide C

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

6 (34757505 - 34773857)

Ensembl ID

ENSG00000124562  (ver. 103.38)

Orthologs

Mouse Snrpc: ENSMUSG00000024217

UniProt

P09234

neXtProt

NX_P09234

Human splice variants
Mouse splice variants

Protein structure