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Protein structure
NHP2
NHP2 ribonucleoproteinFLJ20479, NOLA2
This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
Top validated antibodies |
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| Proteintech Group |  15128-1-AP |
8 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 15128-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| NovoPro Bioscience Inc. | 113179 |
Polyclonal |
WB
EL
ICC
IP
IHC
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| Wuhan Fine Biotech Co., Ltd. | FNab05727 |
Polyclonal |
WB
EL
ICC
IP
IHC
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| Novus Biologicals | 45810002 |
2 references | Polyclonal |
WB
EL
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