2280

antibody from Cell Signaling Technology, Inc

Targeting: RPTOR KIAA1303, KOG1, Mip1, raptor

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

2280

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#2280, RRID:AB_561245

Product name

Raptor (24C12) Rabbit mAb

Antibody type

Monoclonal

Reactivity

Human, Mouse, Rat, Simian

Host

Rabbit

Storage

-20°C

References

Submitted references

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Nature 2014 Apr 24;508(7497):541-5

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The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.

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Science signaling 2012 Jun 12;5(228):ra42

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mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

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Cell 2011 May 13;145(4):607-21

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Science signaling 2011 Feb 22;4(161):ra10

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Acetaminophen improves protein translational signaling in aged skeletal muscle.

Wu M, Liu H, Fannin J, Katta A, Wang Y, Arvapalli RK, Paturi S, Karkala SK, Rice KM, Blough ER
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The association of AMPK with ULK1 regulates autophagy.

Lee JW, Park S, Takahashi Y, Wang HG
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Functional interaction of mammalian target of rapamycin complexes in regulating mammalian cell size and cell cycle.

Rosner M, Fuchs C, Siegel N, Valli A, Hengstschläger M
Human molecular genetics 2009 Sep 1;18(17):3298-310

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Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.

Hasumi Y, Baba M, Ajima R, Hasumi H, Valera VA, Klein ME, Haines DC, Merino MJ, Hong SB, Yamaguchi TP, Schmidt LS, Linehan WM
Proceedings of the National Academy of Sciences of the United States of America 2009 Nov 3;106(44):18722-7

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CCL2 is a negative regulator of AMP-activated protein kinase to sustain mTOR complex-1 activation, survivin expression, and cell survival in human prostate cancer PC3 cells.

Roca H, Varsos ZS, Pienta KJ
Neoplasia (New York, N.Y.) 2009 Dec;11(12):1309-17

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Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, Guan JL, Oshiro N, Mizushima N
Molecular biology of the cell 2009 Apr;20(7):1981-91