MGME1

Mitochondrial genome maintenance exonuclease 1

bA504H3.4, C20orf72, DDK1

The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]

Ensembl	UniProt	RefSeq	Entrez
ENST00000377704 ENSP00000366933	Q5QPE7	NP_001297268.1 NP_001297268	MGME1 92667
ENST00000377709 ENSP00000366938	Q5QPE8	NP_001350667.1 NP_001350667	MGME1 92667
ENST00000377710 ENSP00000366939	Q9BQP7.148 Q9BQP7	NP_443097.1 NP_443097 NP_001297267.1 NP_001297267	MGME1 92667

Ensembl	UniProt	RefSeq	Entrez
ENSMUST00000028910 ENSMUSP00000028910	Q9CXC3.121 Q9CXC3	NP_001342617.1 NP_001342617 NP_001276560.1 NP_001276560 NP_083260.1 NP_083260	Mgme1 74528
ENSMUST00000110027 ENSMUSP00000105654	Q9CXC3.121 Q9CXC3	NP_001276559.1 NP_001276559	Mgme1 74528
ENSMUST00000110028 ENSMUSP00000105655	Q9CXC3.121 Q9CXC3		Mgme1 74528

More gene data

Top validated antibodies
Atlas Antibodies	HPA040913	3 references	Polyclonal	WB ICC IHC
Novus Biologicals	NBP1-91726	3 references	Polyclonal	WB ICC IHC
Acris Antibodies GmbH	AP50583PU-N		Polyclonal	WB EL IHC FC
Invitrogen Antibodies	PA5-59348		Polyclonal	WB ICC IHC
Abnova Corporation	PAB27888		Polyclonal	WB ICC IHC

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Data in Antibodypedia (inconclusive)

Recommended by provider

84 antibodies from 18 providers.

Show Additional Columns

	Antibody	Refs	Type
Novus Biologicals 3 antibodies
	NBP1-91726	3	Polyclonal
	NBP2-83203-0.1ml		Polyclonal

Atlas Antibodies 1 antibody
	HPA040913	3	Polyclonal

Acris Antibodies GmbH 1 antibody
	AP50583PU-N		Polyclonal

Invitrogen Antibodies 7 antibodies
	PA5-59348		Polyclonal
	PA5-118060		Polyclonal

Abnova Corporation 2 antibodies
	PAB27888		Polyclonal
	PAB24160		Polyclonal

antibodies-online 32 antibodies
	ABIN4286324		Polyclonal
	ABIN5649661		Polyclonal

Proteintech Group 2 antibodies
	23178-1-AP		Polyclonal
	67468-1-Ig		Monoclonal

Biorbyt 6 antibodies
	orb1419825		Polyclonal
	orb698968		Polyclonal

Cusabio Biotech Co., Ltd 4 antibodies
	CSB-PA880084LA01HU		Polyclonal
	CSB-PA880084LB01HU		Polyclonal

NovoPro Bioscience Inc. 1 antibody
	112602		Polyclonal

Wuhan Fine Biotech Co., Ltd. 1 antibody
	FNab05168		Polyclonal

LSBio 11 antibodies
	LS-C379791		Polyclonal
	LS-C830992		Polyclonal

OriGene 4 antibodies
	TA351774		Polyclonal
	TA333572		Polyclonal

Aviva Systems Biology 1 antibody
	ARP69139_P050		Polyclonal

Creative Diagnostics 2 antibodies
	CABT-BL699		Polyclonal
	CABT-BL698		Polyclonal

Abbexa 4 antibodies
	abx302859		Polyclonal
	abx311506		Polyclonal

MyBioSource 1 antibody
	MBS2516969		Polyclonal

GeneTex 1 antibody
	GTX120418		Polyclonal

MGME1

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MGME1

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