PPP4R4

The protein encoded by this gene is a HEAT-like repeat-containing protein. The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins. Arrays of HEAT repeats form a rod-like helical structure and appear to function as protein-protein interaction surfaces. The repeat-containing region of this protein has some similarity to the constant regulatory domain of the protein phosphatase 2A PR65/A subunit. The encoded protein binds protein serine/threonine phosphatase 4c in the cytoplasm. [provided by RefSeq, Jan 2017]

Description

Protein phosphatase 4 regulatory subunit 4

Tissue specificity

Tissue enhanced (retina, testis)

Subcell location

Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

14 (94146128 - 94279734)

Ensembl ID

ENSG00000119698  (ver. 103.38)

Orthologs

Mouse Ppp4r4: ENSMUSG00000021209

UniProt

Q6NUP7

neXtProt

NX_Q6NUP7

Human splice variants
Mouse splice variants

Protein structure