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Protein structure
WDR11
WD repeat domain 11BRWD2, DR11, FLJ10506, HH14, KIAA1351, SRI1, WDR15
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  44460002 |
2 references | Polyclonal |
WB
EL
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| antibodies-online | ABIN2840446 |
1 references | Polyclonal |
WB
FC
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| Invitrogen Antibodies | PA5-25619 |
1 references | Polyclonal |
WB
FC
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| Biorbyt | orb1275747 |
Polyclonal |
WB
EL
IHC
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| Abgent | AP5715c |
Polyclonal |
WB
FC
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