ARL16

The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). This protein has been shown to have an inhibitory role in the cellular antiviral response. This gene product interacts with the C-terminal domain of the DEXD/H-box helicase 58 (DDX58) gene product. This interaction was found to suppress the association between the DDX58 gene product and RNA, thereby negatively regulating the activity of the DDX58 gene product. [provided by RefSeq, Jul 2016]

Description

ADP ribosylation factor like GTPase 16

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Predicted intracellular proteins

Chromosome

17 (81681187 - 81683797)

Ensembl ID

ENSG00000214087  (ver. 103.38)

Orthologs

Mouse Arl16: ENSMUSG00000057594

UniProt

 

neXtProt

 

Human splice variants
Mouse splice variants

Protein structure