Tissue expression
Cell line expression
Protein structure
NXF3
Nuclear RNA export factor 3This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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GeneTex | GTX116398 | 1 references | Polyclonal |
WB
ICC
IHC
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Novus Biologicals | H00056000-M06 | Monoclonal |
WB
EL
ICC
IHC |
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antibodies-online | ABIN557704 | Polyclonal |
WB
ICC
IHC
|
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Abnova Corporation | H00056000-M06 | Monoclonal |
EL
ICC
IHC
|
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LSBio | LS-C31687 | Polyclonal |
WB
IHC |
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