AF6294

antibody from Novus Biologicals

Targeting: ONECUT2 OC-2

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

AF6294

Provider

Novus Biologicals

Product name

Sheep Polyclonal ONECUT2/OC-2 Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects human ONECUT2/OC-2 in direct ELISAs. In direct ELISAs, approximately 10% cross-reactivity with recombinant human ONECUT1 is observed.

Reactivity

Human

Host

Sheep

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits.

Toch M, Harris A, Schakman O, Kondratskaya E, Boulland JL, Dauguet N, Debrulle S, Baudouin C, Hidalgo-Figueroa M, Mu X, Gow A, Glover JC, Tissir F, Clotman F
Scientific reports 2020 Jan 22;10(1):996

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Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma.

Wei R, Ren X, Kong H, Lv Z, Chen Y, Tang Y, Wang Y, Xiao L, Yu T, Hacibekiroglu S, Liang C, Nagy A, Bremner R, Chen D
JCI insight 2019 Nov 14;4(22)

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Unique Gene Expression Signatures in the Intestinal Mucosa and Organoids Derived from Germ-Free and Monoassociated Mice.

Janeckova L, Kostovcikova K, Svec J, Stastna M, Strnad H, Kolar M, Hudcovic T, Stancikova J, Tureckova J, Baloghova N, Sloncova E, Galuskova K, Tlaskalova-Hogenova H, Korinek V
International journal of molecular sciences 2019 Mar 29;20(7)

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Rb is required for retinal angiogenesis and lamination.

Zhou Y, Wei R, Zhang L, Chen Y, Lu S, Liang C, Wang Y, Xiao L, Zhang J, Bremner R, Chen D
Cell death & disease 2018 Mar 6;9(3):370

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The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development.

Kabayiza KU, Masgutova G, Harris A, Rucchin V, Jacob B, Clotman F
Frontiers in molecular neuroscience 2017;10:157

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A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells.

Velasco S, Ibrahim MM, Kakumanu A, Garipler G, Aydin B, Al-Sayegh MA, Hirsekorn A, Abdul-Rahman F, Satija R, Ohler U, Mahony S, Mazzoni EO
Cell stem cell 2017 Feb 2;20(2):205-217.e8