BS7689

antibody from Bioworld Technology, Inc

Targeting: DAOA G72

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS7689

Provider

Bioworld Technology, Inc

Product name

DAOA polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human DAOA.

Description

D-amino acid oxidase (DAAO) metabolizes exogenous D-amino acids that accumulate during aging and modulates the level of D-serine in the brain, acting as a detoxifying agent. DAAO is specific for the D-configuration of amino acids and exhibits a preference for those with small, hydrophobic side chains and polar, aromatic and basic functional groups. D-amino acid oxidase activator (G72) associates with and activates DAAO. This 157 amino acid protein localizes to the Golgi apparatus. The gene encoding for the protein, known as DAOA, maps to chromosome 13q33.2-13q34. G72 is expressed in amygdala, spinal cord and testis. The G72 protein, together with the associated protein DAAO, is often implicated in schizophrenia. An overexpression of the G72 protein can be detected in schizophrenic brain samples.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.