130-00012-200

antibody from RayBiotech, Inc.

Targeting: NPW PPL8

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

130-00012-200

Provider

RayBiotech, Inc.

Proper citation

RayBiotech Cat#130-00012-200, RRID:AB_11218633

Product name

Rabbit Anti-Human Neuropeptide W

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Neuropeptide W is an endogenous peptide ligand for GPR8, a G protein-coupled receptor. This protein is detected at high levels in the substantia nigra, fetal kidney and trachea; at lower levels in testis, uterus, ovary and placenta, and not detectable in many regions of the central nervous system. It is also detected at high levels in lymphoblastic leukemia and colorectal adenocarcinoma. The product of this gene is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. This antibody was produced from a rabbit immunized with this peptide conjugated with KLH. The IgG fraction was purified from rabbit serum by Protein G affinity chromatography

Reactivity

Human

Host

Chicken/Avian

Antigen sequence

This antibody was produced from a r
abbit immunized with this peptide c
onjugated with KLH. The IgG fractio
n was purified from rabbit serum by
Protein G affinity chromatography


Isotype

IgG

Vial size

200 µg

Handling

Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1 x PBS to a final concentration of 1 mg/ml.