Antibody data
- Antibody Data
- Antigen structure
- References [71]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
- Flow cytometry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- AF3628 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse/Rat CD31/PECAM-1 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse CD31/PECAM-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human CD31 and recombinant porcine CD31 is observed. Detects mouse CD31 and rat CD31 in flow cytometry.
- Reactivity
- Mouse, Rat
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
Q08481
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Endothelial cells are a source of Nestin expression in Pulmonary Arterial Hypertension.
Transfusion of Resting Platelets Reduces Brain Hemorrhage After Intracerebral Hemorrhage and tPA-Induced Hemorrhage After Cerebral Ischemia.
Semaphorin-3A protects against neointimal hyperplasia after vascular injury.
Endothelial repair is dependent on CD11c+ leukocytes to establish regrowing endothelial sheets with high cellular density.
PU.1 controls fibroblast polarization and tissue fibrosis.
Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation.
Tumor pH and Protein Concentration Contribute to the Signal of Amide Proton Transfer Magnetic Resonance Imaging.
Dosimetric evaluation of radionuclides for VCAM-1-targeted radionuclide therapy of early brain metastases.
Differential role of Interleukin-1 and Interleukin-6 in K-Ras-driven pancreatic carcinoma undergoing mesenchymal transition.
Pentoxifylline decreases post-operative intra-abdominal adhesion formation in an animal model.
Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells.
Peripheral myeloid cells contribute to brain injury in male neonatal mice.
Angiopoietin/Tie2 Axis Regulates the Age-at-Injury Cerebrovascular Response to Traumatic Brain Injury.
Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6+ cancer cell and macrophage polarization.
Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier.
Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling.
Radiation-induced premature cellular senescence involved in glomerular diseases in rats.
Positive-Feedback Regulation of Subchondral H-Type Vessel Formation by Chondrocyte Promotes Osteoarthritis Development in Mice.
A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease.
Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice.
cxcl12-engineered endothelial progenitor cells enhance neurogenesis and angiogenesis after ischemic brain injury in mice.
Gellan Gum-based luminal fillers for peripheral nerve regeneration: an in vivo study in the rat sciatic nerve repair model.
Intratumoral administration of IL2- and TNF-based fusion proteins cures cancer without establishing protective immunity.
Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal.
Local delivery of tetramethylpyrazine eliminates the senescent phenotype of bone marrow mesenchymal stromal cells and creates an anti-inflammatory and angiogenic environment in aging mice.
Attenuation of Retinal Vascular Development in Neonatal Mice Subjected to Hypoxic-Ischemic Encephalopathy.
UHRF1 epigenetically orchestrates smooth muscle cell plasticity in arterial disease.
KSHV-induced ligand mediated activation of PDGF receptor-alpha drives Kaposi's sarcomagenesis.
Syndecan-1 induction in lung microenvironment supports the establishment of breast tumor metastases.
Characterization of multi-cellular dynamics of angiogenesis and vascular remodelling by intravital imaging of the wounded mouse cornea.
Multicolor quantitative confocal imaging cytometry.
Type I interferons instigate fetal demise after Zika virus infection.
Hindlimb Ischemia Impairs Endothelial Recovery and Increases Neointimal Proliferation in the Carotid Artery.
Bones in human CYP26B1 deficiency and rats with hypervitaminosis A phenocopy Vegfa overexpression.
Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA.
SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells.
Mesenchymal stem cells ameliorate hyperglycemia-induced endothelial injury through modulation of mitophagy.
The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Resident Arterial Cells and Circulating Bone Marrow-Derived Cells both Contribute to Intimal Hyperplasia in a Rat Allograft Carotid Transplantation Model.
Excessive dietary intake of vitamin A reduces skull bone thickness in mice.
Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice.
Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents.
Natural compound bavachalcone promotes the differentiation of endothelial progenitor cells and neovascularization through the RORα-erythropoietin-AMPK axis.
Brachyury drives formation of a distinct vascular branchpoint critical for fetal-placental arterial union in the mouse gastrula.
Impacts of femoral artery and vein excision versus femoral artery excision on the hindlimb ischemic model in CD-1 mice.
Gene therapy for a mouse model of glucose transporter-1 deficiency syndrome.
Immunofluorescence reveals unusual patterns of labelling for connexin43 localized to calbindin-D28K-positive interstitial cells in the pineal gland.
Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues.
Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling.
Silencing of galectin-1 inhibits retinal neovascularization and ameliorates retinal hypoxia in a murine model of oxygen-induced ischemic retinopathy.
Coronary angiogenic effect of long-term administration of Nigella sativa.
Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.
Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development.
Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells.
TLR2-mediated leukocyte trafficking to the developing brain.
Integrin β1 controls VE-cadherin localization and blood vessel stability.
The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis.
The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression.
Periadventitial application of rapamycin-loaded nanoparticles produces sustained inhibition of vascular restenosis.
Formation of fenestrae in murine liver sinusoids depends on plasmalemma vesicle-associated protein and is required for lipoprotein passage.
ITE and TCDD differentially regulate the vascular remodeling of rat placenta via the activation of AhR.
Peroxisome proliferator-activated receptor α protects capillary pericytes in the retina.
Anticancer effects of gemcitabine are enhanced by co-administered iRGD peptide in murine pancreatic cancer models that overexpressed neuropilin-1.
MicroRNA-210 overexpression induces angiogenesis and neurogenesis in the normal adult mouse brain.
Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.
Characterization of the adverse effects of nicotine on placental development: in vivo and in vitro studies.
Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-β signaling pathways.
TGF-β mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells.
The critical role of agrin in the hematopoietic stem cell niche.
Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth.
Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin.
Bhagwani AR, Hultman S, Farkas D, Moncayo R, Dandamudi K, Zadu AK, Cool CD, Farkas L
PloS one 2019;14(3):e0213890
PloS one 2019;14(3):e0213890
Transfusion of Resting Platelets Reduces Brain Hemorrhage After Intracerebral Hemorrhage and tPA-Induced Hemorrhage After Cerebral Ischemia.
Luo H, Wei L, Lu L, Kang L, Cao Y, Yang X, Bai X, Fan W, Zhao BQ
Frontiers in neuroscience 2019;13:338
Frontiers in neuroscience 2019;13:338
Semaphorin-3A protects against neointimal hyperplasia after vascular injury.
Wu JH, Zhou YF, Hong CD, Chen AQ, Luo Y, Mao L, Xia YP, He QW, Jin HJ, Huang M, Li YN, Hu B
EBioMedicine 2019 Jan;39:95-108
EBioMedicine 2019 Jan;39:95-108
Endothelial repair is dependent on CD11c+ leukocytes to establish regrowing endothelial sheets with high cellular density.
Yrlid U, Holm M, Levin M, Alsén S, Lindbom M, Glise L, Bergh N, Borén J, Fogelstrand P
Journal of leukocyte biology 2019 Jan;105(1):195-202
Journal of leukocyte biology 2019 Jan;105(1):195-202
PU.1 controls fibroblast polarization and tissue fibrosis.
Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, Weber S, Matei AE, Chen CW, Maier C, Karouzakis E, Kiener HP, Pachera E, Dees C, Beyer C, Daniel C, Gelse K, Kremer AE, Naschberger E, Stürzl M, Butter F, Sticherling M, Finotto S, Kreuter A, Kaplan MH, Jüngel A, Gay S, Nutt SL, Boykin DW, Poon GMK, Distler O, Schett G, Distler JHW, Ramming A
Nature 2019 Feb;566(7744):344-349
Nature 2019 Feb;566(7744):344-349
Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation.
Romeo SG, Alawi KM, Rodrigues J, Singh A, Kusumbe AP, Ramasamy SK
Nature cell biology 2019 Apr;21(4):430-441
Nature cell biology 2019 Apr;21(4):430-441
Tumor pH and Protein Concentration Contribute to the Signal of Amide Proton Transfer Magnetic Resonance Imaging.
Ray KJ, Simard MA, Larkin JR, Coates J, Kinchesh P, Smart SC, Higgins GS, Chappell MA, Sibson NR
Cancer research 2019 Apr 1;79(7):1343-1352
Cancer research 2019 Apr 1;79(7):1343-1352
Dosimetric evaluation of radionuclides for VCAM-1-targeted radionuclide therapy of early brain metastases.
Falzone N, Ackerman NL, Rosales LF, Bernal MA, Liu X, Peeters SG, Soto MS, Corroyer-Dulmont A, Bernaudin M, Grimoin E, Touzani O, Sibson NR, Vallis KA
Theranostics 2018;8(1):292-303
Theranostics 2018;8(1):292-303
Differential role of Interleukin-1 and Interleukin-6 in K-Ras-driven pancreatic carcinoma undergoing mesenchymal transition.
Siddiqui I, Erreni M, Kamal MA, Porta C, Marchesi F, Pesce S, Pasqualini F, Schiarea S, Chiabrando C, Mantovani A, Allavena P
Oncoimmunology 2018;7(2):e1388485
Oncoimmunology 2018;7(2):e1388485
Pentoxifylline decreases post-operative intra-abdominal adhesion formation in an animal model.
Yang YL, Lee MG, Lee CC, Su PI, Chi CY, Liu CH, Wu MC, Yen ZS, Chen SC
PeerJ 2018;6:e5434
PeerJ 2018;6:e5434
Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells.
Stone OA, El-Brolosy M, Wilhelm K, Liu X, Romão AM, Grillo E, Lai JKH, Günther S, Jeratsch S, Kuenne C, Lee IC, Braun T, Santoro MM, Locasale JW, Potente M, Stainier DYR
Nature communications 2018 Oct 9;9(1):4077
Nature communications 2018 Oct 9;9(1):4077
Peripheral myeloid cells contribute to brain injury in male neonatal mice.
Smith PLP, Mottahedin A, Svedin P, Mohn CJ, Hagberg H, Ek J, Mallard C
Journal of neuroinflammation 2018 Oct 30;15(1):301
Journal of neuroinflammation 2018 Oct 30;15(1):301
Angiopoietin/Tie2 Axis Regulates the Age-at-Injury Cerebrovascular Response to Traumatic Brain Injury.
Brickler TR, Hazy A, Guilhaume Correa F, Dai R, Kowalski EJA, Dickerson R, Chen J, Wang X, Morton PD, Whittington A, Ahmed A, Theus MH
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Nov 7;38(45):9618-9634
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Nov 7;38(45):9618-9634
Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6+ cancer cell and macrophage polarization.
Choi SH, Kim AR, Nam JK, Kim JM, Kim JY, Seo HR, Lee HJ, Cho J, Lee YJ
Nature communications 2018 Nov 30;9(1):5108
Nature communications 2018 Nov 30;9(1):5108
Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier.
Mäe MA, Li T, Bertuzzi G, Raschperger E, Vanlandewijck M, He L, Nahar K, Dalheim A, Hofmann JJ, Laviña B, Keller A, Betsholtz C, Genové G
Scientific reports 2018 Nov 29;8(1):17462
Scientific reports 2018 Nov 29;8(1):17462
Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling.
Hübner K, Cabochette P, Diéguez-Hurtado R, Wiesner C, Wakayama Y, Grassme KS, Hubert M, Guenther S, Belting HG, Affolter M, Adams RH, Vanhollebeke B, Herzog W
Nature communications 2018 Nov 19;9(1):4860
Nature communications 2018 Nov 19;9(1):4860
Radiation-induced premature cellular senescence involved in glomerular diseases in rats.
Aratani S, Tagawa M, Nagasaka S, Sakai Y, Shimizu A, Tsuruoka S
Scientific reports 2018 Nov 14;8(1):16812
Scientific reports 2018 Nov 14;8(1):16812
Positive-Feedback Regulation of Subchondral H-Type Vessel Formation by Chondrocyte Promotes Osteoarthritis Development in Mice.
Lu J, Zhang H, Cai D, Zeng C, Lai P, Shao Y, Fang H, Li D, Ouyang J, Zhao C, Xie D, Huang B, Yang J, Jiang Y, Bai X
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2018 May;33(5):909-920
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2018 May;33(5):909-920
A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease.
Wang X, Philip VM, Ananda G, White CC, Malhotra A, Michalski PJ, Karuturi KRM, Chintalapudi SR, Acklin C, Sasner M, Bennett DA, De Jager PL, Howell GR, Carter GW
Genetics 2018 May;209(1):51-64
Genetics 2018 May;209(1):51-64
Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice.
Cheng Z, Wang L, Qu M, Liang H, Li W, Li Y, Deng L, Zhang Z, Yang GY
Journal of neuroinflammation 2018 May 3;15(1):135
Journal of neuroinflammation 2018 May 3;15(1):135
cxcl12-engineered endothelial progenitor cells enhance neurogenesis and angiogenesis after ischemic brain injury in mice.
Li Y, Chang S, Li W, Tang G, Ma Y, Liu Y, Yuan F, Zhang Z, Yang GY, Wang Y
Stem cell research & therapy 2018 May 11;9(1):139
Stem cell research & therapy 2018 May 11;9(1):139
Gellan Gum-based luminal fillers for peripheral nerve regeneration: an in vivo study in the rat sciatic nerve repair model.
Carvalho CR, Wrobel S, Meyer C, Brandenberger C, Cengiz IF, López-Cebral R, Silva-Correia J, Ronchi G, Reis RL, Grothe C, Oliveira JM, Haastert-Talini K
Biomaterials science 2018 May 1;6(5):1059-1075
Biomaterials science 2018 May 1;6(5):1059-1075
Intratumoral administration of IL2- and TNF-based fusion proteins cures cancer without establishing protective immunity.
Ziffels B, Pretto F, Neri D
Immunotherapy 2018 Mar;10(3):177-188
Immunotherapy 2018 Mar;10(3):177-188
Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal.
Rayagiri SS, Ranaldi D, Raven A, Mohamad Azhar NIF, Lefebvre O, Zammit PS, Borycki AG
Nature communications 2018 Mar 14;9(1):1075
Nature communications 2018 Mar 14;9(1):1075
Local delivery of tetramethylpyrazine eliminates the senescent phenotype of bone marrow mesenchymal stromal cells and creates an anti-inflammatory and angiogenic environment in aging mice.
Gao B, Lin X, Jing H, Fan J, Ji C, Jie Q, Zheng C, Wang D, Xu X, Hu Y, Lu W, Luo Z, Yang L
Aging cell 2018 Jun;17(3):e12741
Aging cell 2018 Jun;17(3):e12741
Attenuation of Retinal Vascular Development in Neonatal Mice Subjected to Hypoxic-Ischemic Encephalopathy.
Zaitoun IS, Cikla U, Zafer D, Udho E, Almomani R, Suscha A, Cengiz P, Sorenson CM, Sheibani N
Scientific reports 2018 Jun 15;8(1):9166
Scientific reports 2018 Jun 15;8(1):9166
UHRF1 epigenetically orchestrates smooth muscle cell plasticity in arterial disease.
Elia L, Kunderfranco P, Carullo P, Vacchiano M, Farina FM, Hall IF, Mantero S, Panico C, Papait R, Condorelli G, Quintavalle M
The Journal of clinical investigation 2018 Jun 1;128(6):2473-2486
The Journal of clinical investigation 2018 Jun 1;128(6):2473-2486
KSHV-induced ligand mediated activation of PDGF receptor-alpha drives Kaposi's sarcomagenesis.
Cavallin LE, Ma Q, Naipauer J, Gupta S, Kurian M, Locatelli P, Romanelli P, Nadji M, Goldschmidt-Clermont PJ, Mesri EA
PLoS pathogens 2018 Jul;14(7):e1007175
PLoS pathogens 2018 Jul;14(7):e1007175
Syndecan-1 induction in lung microenvironment supports the establishment of breast tumor metastases.
Chute C, Yang X, Meyer K, Yang N, O'Neil K, Kasza I, Eliceiri K, Alexander C, Friedl A
Breast cancer research : BCR 2018 Jul 5;20(1):66
Breast cancer research : BCR 2018 Jul 5;20(1):66
Characterization of multi-cellular dynamics of angiogenesis and vascular remodelling by intravital imaging of the wounded mouse cornea.
Wang Y, Jin Y, Laviña B, Jakobsson L
Scientific reports 2018 Jul 13;8(1):10672
Scientific reports 2018 Jul 13;8(1):10672
Multicolor quantitative confocal imaging cytometry.
Coutu DL, Kokkaliaris KD, Kunz L, Schroeder T
Nature methods 2018 Jan;15(1):39-46
Nature methods 2018 Jan;15(1):39-46
Type I interferons instigate fetal demise after Zika virus infection.
Yockey LJ, Jurado KA, Arora N, Millet A, Rakib T, Milano KM, Hastings AK, Fikrig E, Kong Y, Horvath TL, Weatherbee S, Kliman HJ, Coyne CB, Iwasaki A
Science immunology 2018 Jan 5;3(19)
Science immunology 2018 Jan 5;3(19)
Hindlimb Ischemia Impairs Endothelial Recovery and Increases Neointimal Proliferation in the Carotid Artery.
Sorrentino S, Iaconetti C, De Rosa S, Polimeni A, Sabatino J, Gareri C, Passafaro F, Mancuso T, Tammè L, Mignogna C, Camastra C, Esposito G, Curcio A, Torella D, Indolfi C
Scientific reports 2018 Jan 15;8(1):761
Scientific reports 2018 Jan 15;8(1):761
Bones in human CYP26B1 deficiency and rats with hypervitaminosis A phenocopy Vegfa overexpression.
Lind T, Lugano R, Gustafson AM, Norgård M, van Haeringen A, Dimberg A, Melhus H, Robertson SP, Andersson G
Bone reports 2018 Dec;9:27-36
Bone reports 2018 Dec;9:27-36
Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA.
Scavuzzo MA, Chmielowiec J, Yang D, Wamble K, Chaboub LS, Duraine L, Tepe B, Glasgow SM, Arenkiel BR, Brou C, Deneen B, Borowiak M
Cell reports 2018 Dec 26;25(13):3811-3827.e7
Cell reports 2018 Dec 26;25(13):3811-3827.e7
SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells.
Chagraoui H, Kristiansen MS, Ruiz JP, Serra-Barros A, Richter J, Hall-Ponselé E, Gray N, Waithe D, Clark K, Hublitz P, Repapi E, Otto G, Sopp P, Taylor S, Thongjuea S, Vyas P, Porcher C
Nature communications 2018 Dec 18;9(1):5375
Nature communications 2018 Dec 18;9(1):5375
Mesenchymal stem cells ameliorate hyperglycemia-induced endothelial injury through modulation of mitophagy.
Zhu W, Yuan Y, Liao G, Li L, Liu J, Chen Y, Zhang J, Cheng J, Lu Y
Cell death & disease 2018 Aug 6;9(8):837
Cell death & disease 2018 Aug 6;9(8):837
The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Zehender A, Huang J, Györfi AH, Matei AE, Trinh-Minh T, Xu X, Li YN, Chen CW, Lin J, Dees C, Beyer C, Gelse K, Zhang ZY, Bergmann C, Ramming A, Birchmeier W, Distler O, Schett G, Distler JHW
Nature communications 2018 Aug 14;9(1):3259
Nature communications 2018 Aug 14;9(1):3259
Resident Arterial Cells and Circulating Bone Marrow-Derived Cells both Contribute to Intimal Hyperplasia in a Rat Allograft Carotid Transplantation Model.
He Y, Xu X, Zhu T, Tang M, Mei J, Si Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(4):1303-1312
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(4):1303-1312
Excessive dietary intake of vitamin A reduces skull bone thickness in mice.
Lind T, Öhman C, Calounova G, Rasmusson A, Andersson G, Pejler G, Melhus H
PloS one 2017;12(4):e0176217
PloS one 2017;12(4):e0176217
Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice.
Aoyagi-Scharber M, Crippen-Harmon D, Lawrence R, Vincelette J, Yogalingam G, Prill H, Yip BK, Baridon B, Vitelli C, Lee A, Gorostiza O, Adintori EG, Minto WC, Van Vleet JL, Yates B, Rigney S, Christianson TM, Tiger PMN, Lo MJ, Holtzinger J, Fitzpatrick PA, LeBowitz JH, Bullens S, Crawford BE, Bunting S
Molecular therapy. Methods & clinical development 2017 Sep 15;6:43-53
Molecular therapy. Methods & clinical development 2017 Sep 15;6:43-53
Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents.
Chen M, Lei X, Shi C, Huang M, Li X, Wu B, Li Z, Han W, Du B, Hu J, Nie Q, Mai W, Ma N, Xu N, Zhang X, Fan C, Hong A, Xia M, Luo L, Ma A, Li H, Yu Q, Chen H, Zhang D, Ye W
The Journal of clinical investigation 2017 Oct 2;127(10):3689-3701
The Journal of clinical investigation 2017 Oct 2;127(10):3689-3701
Natural compound bavachalcone promotes the differentiation of endothelial progenitor cells and neovascularization through the RORα-erythropoietin-AMPK axis.
Ling S, Ni RZ, Yuan Y, Dang YQ, Zhou QM, Liang S, Guo F, Feng W, Chen Y, Ikeda K, Yamori Y, Xu JW
Oncotarget 2017 Oct 17;8(49):86188-86205
Oncotarget 2017 Oct 17;8(49):86188-86205
Brachyury drives formation of a distinct vascular branchpoint critical for fetal-placental arterial union in the mouse gastrula.
Rodriguez AM, Jin DX, Wolfe AD, Mikedis MM, Wierenga L, Hashmi MP, Viebahn C, Downs KM
Developmental biology 2017 May 15;425(2):208-222
Developmental biology 2017 May 15;425(2):208-222
Impacts of femoral artery and vein excision versus femoral artery excision on the hindlimb ischemic model in CD-1 mice.
Chen M, Fan H, Ledford BT, Farah Z, Barron C, Liu Z, He JQ
Microvascular research 2017 Mar;110:48-55
Microvascular research 2017 Mar;110:48-55
Gene therapy for a mouse model of glucose transporter-1 deficiency syndrome.
Nakamura S, Osaka H, Muramatsu SI, Takino N, Ito M, Aoki S, Jimbo EF, Shimazaki K, Onaka T, Ohtsuki S, Terasaki T, Yamagata T
Molecular genetics and metabolism reports 2017 Mar;10:67-74
Molecular genetics and metabolism reports 2017 Mar;10:67-74
Immunofluorescence reveals unusual patterns of labelling for connexin43 localized to calbindin-D28K-positive interstitial cells in the pineal gland.
Tsao DD, Wang SG, Lynn BD, Nagy JI
The European journal of neuroscience 2017 Jun;45(12):1553-1569
The European journal of neuroscience 2017 Jun;45(12):1553-1569
Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues.
Sugden WW, Meissner R, Aegerter-Wilmsen T, Tsaryk R, Leonard EV, Bussmann J, Hamm MJ, Herzog W, Jin Y, Jakobsson L, Denz C, Siekmann AF
Nature cell biology 2017 Jun;19(6):653-665
Nature cell biology 2017 Jun;19(6):653-665
Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling.
Jin Y, Muhl L, Burmakin M, Wang Y, Duchez AC, Betsholtz C, Arthur HM, Jakobsson L
Nature cell biology 2017 Jun;19(6):639-652
Nature cell biology 2017 Jun;19(6):639-652
Silencing of galectin-1 inhibits retinal neovascularization and ameliorates retinal hypoxia in a murine model of oxygen-induced ischemic retinopathy.
Yang N, Zhang W, He T, Xing Y
Experimental eye research 2017 Jun;159:1-15
Experimental eye research 2017 Jun;159:1-15
Coronary angiogenic effect of long-term administration of Nigella sativa.
Al Asoom LI
BMC complementary and alternative medicine 2017 Jun 13;17(1):308
BMC complementary and alternative medicine 2017 Jun 13;17(1):308
Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.
Schneider RK, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, Van Strien PMH, Bindels EM, Heckl D, Büsche G, Fleck D, Müller-Newen G, Wongboonsin J, Ventura Ferreira M, Puelles VG, Saez-Rodriguez J, Ebert BL, Humphreys BD, Kramann R
Cell stem cell 2017 Jun 1;20(6):785-800.e8
Cell stem cell 2017 Jun 1;20(6):785-800.e8
Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development.
Gerl K, Steppan D, Fuchs M, Wagner C, Willam C, Kurtz A, Kurt B
The American journal of pathology 2017 Jul;187(7):1496-1511
The American journal of pathology 2017 Jul;187(7):1496-1511
Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells.
Krueger PD, Narayanan S, Surette FA, Brown MG, Sung SJ, Hahn YS
Journal of leukocyte biology 2017 Jan;101(1):329-338
Journal of leukocyte biology 2017 Jan;101(1):329-338
TLR2-mediated leukocyte trafficking to the developing brain.
Mottahedin A, Smith PL, Hagberg H, Ek CJ, Mallard C
Journal of leukocyte biology 2017 Jan;101(1):297-305
Journal of leukocyte biology 2017 Jan;101(1):297-305
Integrin β1 controls VE-cadherin localization and blood vessel stability.
Yamamoto H, Ehling M, Kato K, Kanai K, van Lessen M, Frye M, Zeuschner D, Nakayama M, Vestweber D, Adams RH
Nature communications 2015 Mar 10;6:6429
Nature communications 2015 Mar 10;6:6429
The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis.
Prevete N, Liotti F, Visciano C, Marone G, Melillo RM, de Paulis A
Oncogene 2015 Jul;34(29):3826-38
Oncogene 2015 Jul;34(29):3826-38
The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression.
Shi X, Zirbes KM, Rasmussen TL, Ferdous A, Garry MG, Koyano-Nakagawa N, Garry DJ
The Journal of biological chemistry 2015 Apr 10;290(15):9614-25
The Journal of biological chemistry 2015 Apr 10;290(15):9614-25
Periadventitial application of rapamycin-loaded nanoparticles produces sustained inhibition of vascular restenosis.
Shi X, Chen G, Guo LW, Si Y, Zhu M, Pilla S, Liu B, Gong S, Kent KC
PloS one 2014;9(2):e89227
PloS one 2014;9(2):e89227
Formation of fenestrae in murine liver sinusoids depends on plasmalemma vesicle-associated protein and is required for lipoprotein passage.
Herrnberger L, Hennig R, Kremer W, Hellerbrand C, Goepferich A, Kalbitzer HR, Tamm ER
PloS one 2014;9(12):e115005
PloS one 2014;9(12):e115005
ITE and TCDD differentially regulate the vascular remodeling of rat placenta via the activation of AhR.
Wu Y, Chen X, Zhou Q, He Q, Kang J, Zheng J, Wang K, Duan T
PloS one 2014;9(1):e86549
PloS one 2014;9(1):e86549
Peroxisome proliferator-activated receptor α protects capillary pericytes in the retina.
Ding L, Cheng R, Hu Y, Takahashi Y, Jenkins AJ, Keech AC, Humphries KM, Gu X, Elliott MH, Xia X, Ma JX
The American journal of pathology 2014 Oct;184(10):2709-20
The American journal of pathology 2014 Oct;184(10):2709-20
Anticancer effects of gemcitabine are enhanced by co-administered iRGD peptide in murine pancreatic cancer models that overexpressed neuropilin-1.
Akashi Y, Oda T, Ohara Y, Miyamoto R, Kurokawa T, Hashimoto S, Enomoto T, Yamada K, Satake M, Ohkohchi N
British journal of cancer 2014 Mar 18;110(6):1481-7
British journal of cancer 2014 Mar 18;110(6):1481-7
MicroRNA-210 overexpression induces angiogenesis and neurogenesis in the normal adult mouse brain.
Zeng L, He X, Wang Y, Tang Y, Zheng C, Cai H, Liu J, Wang Y, Fu Y, Yang GY
Gene therapy 2014 Jan;21(1):37-43
Gene therapy 2014 Jan;21(1):37-43
Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.
Adini I, Ghosh K, Adini A, Chi ZL, Yoshimura T, Benny O, Connor KM, Rogers MS, Bazinet L, Birsner AE, Bielenberg DR, D'Amato RJ
The Journal of clinical investigation 2014 Jan;124(1):425-36
The Journal of clinical investigation 2014 Jan;124(1):425-36
Characterization of the adverse effects of nicotine on placental development: in vivo and in vitro studies.
Holloway AC, Salomon A, Soares MJ, Garnier V, Raha S, Sergent F, Nicholson CJ, Feige JJ, Benharouga M, Alfaidy N
American journal of physiology. Endocrinology and metabolism 2014 Feb 15;306(4):E443-56
American journal of physiology. Endocrinology and metabolism 2014 Feb 15;306(4):E443-56
Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-β signaling pathways.
Park S, Dimaio TA, Liu W, Wang S, Sorenson CM, Sheibani N
Journal of cell science 2013 Mar 15;126(Pt 6):1392-405
Journal of cell science 2013 Mar 15;126(Pt 6):1392-405
TGF-β mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells.
Shinojima N, Hossain A, Takezaki T, Fueyo J, Gumin J, Gao F, Nwajei F, Marini FC, Andreeff M, Kuratsu J, Lang FF
Cancer research 2013 Apr 1;73(7):2333-44
Cancer research 2013 Apr 1;73(7):2333-44
The critical role of agrin in the hematopoietic stem cell niche.
Mazzon C, Anselmo A, Cibella J, Soldani C, Destro A, Kim N, Roncalli M, Burden SJ, Dustin ML, Sarukhan A, Viola A
Blood 2011 Sep 8;118(10):2733-42
Blood 2011 Sep 8;118(10):2733-42
Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth.
Funa NS, Kriz V, Zang G, Calounova G, Akerblom B, Mares J, Larsson E, Sun Y, Betsholtz C, Welsh M
Cancer research 2009 Mar 1;69(5):2141-8
Cancer research 2009 Mar 1;69(5):2141-8
Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin.
Rebholz B, Haase I, Eckelt B, Paxian S, Flaig MJ, Ghoreschi K, Nedospasov SA, Mailhammer R, Debey-Pascher S, Schultze JL, Weindl G, Förster I, Huss R, Stratis A, Ruzicka T, Röcken M, Pfeffer K, Schmid RM, Rupec RA
Immunity 2007 Aug;27(2):296-307
Immunity 2007 Aug;27(2):296-307
No comments: Submit comment
Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of Mouse CD31/PECAM-1 by Western Blot. Western blot shows lysates of bEnd.3 mouse endothelioma cell line. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for CD31/PECAM-1 at approximately 130 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- CD31/PECAM-1 in bEnd.3 Mouse Cell Line. CD31/PECAM-1 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Goat Anti-Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 493-conjugated Anti-Goat IgG Secondary Antibody (green; Catalog # NL003) and counterstained with DAPI (blue). Specific staining was localized to cell membrane. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- CD31/PECAM-1 in Mouse Embryo. CD31/PECAM-1 was detected in immersion fixed frozen sections of mouse embryo (E13.5) using Goat Anti-Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628) at 10 µg/mL overnight at 4 °C. Tissue was stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (yellow; Catalog # NL001) and counterstained with DAPI (blue). Specific staining was localized to developing endothelium. View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- CD31/PECAM-1 in Mouse Embryo. CD31/PECAM-1 was detected in immersion fixed frozen sections of mouse embryo (14 d.p.c.) using Goat Anti-Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628) at 10 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to developing guts. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.
Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CD31/PECAM-1 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628, filled histogram) or control antibody (Catalog # AB-108-C, open histogram), followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0108).
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CD31/PECAM-1 in Rat Splenocytes by Flow Cytometry. Rat splenocytes were stained with Goat Anti-Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628, filled histogram) or isotype control antibody (Catalog # AB-108-C, open histogram), followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0108).