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Protein structure
MT2A
Metallothionein 2AMT2
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer. [provided by RefSeq, Sep 2017]
Top validated antibodies |
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| Novus Biologicals |  H00004502-M01 |
2 references | Monoclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | PA5-102549 |
1 references | Polyclonal |
WB
IHC
OA
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| antibodies-online | ABIN948154 |
1 references | Monoclonal |
WB
EL
ICC
|
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| Abnova Corporation | H00004502-M01 |
1 references | Monoclonal |
EL
ICC
|
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| Proteintech Group | 20809-1-AP |
1 references | Polyclonal |
EL
IHC
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