ODF1

The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. The human outer dense fibers contains at least 10 major proteins and this gene encodes the main protein. [provided by RefSeq, Jul 2008]

Description

Outer dense fiber of sperm tails 1

Tissue specificity

Tissue enriched (testis)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

8 (102551589 - 102561018)

Ensembl ID

ENSG00000155087  (ver. 103.38)

Orthologs

Mouse Odf1: ENSMUSG00000061923

UniProt

Q14990

neXtProt

NX_Q14990

Human splice variants
Mouse splice variants

Protein structure