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AICDA
Activation induced cytidine deaminaseAID, ARP2, CDA2, HIGM2
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. AICDA is specifically expressed and active in germinal center-like B cells. In the germinal center, AICDA is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. An epigenetic role in neoplastic transformation and lymphoma progression has been experimentally ascribed to AICDA using mouse models. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Jul 2020]
Top validated antibodies |
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| Invitrogen Antibodies |  39-2500 |
24 references | Monoclonal |
WB
EL
IP
IHC
OA
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| Abnova Corporation | PAB12893 |
3 references | Polyclonal |
WB
ICC
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| antibodies-online | ABIN2034576 |
Polyclonal |
WB
ICC
IHC
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| GeneTex | GTX104662 |
Polyclonal |
WB
ICC
IHC
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| LSBio | LS-B16 |
Polyclonal |
WB
EL
ICC
IHC
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