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LearnABIN500314
antibody from antibodies-online
Targeting: NLRP3
AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCU, MWS, NALP3, PYPAF1
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN500314 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) antibody
- Antibody type
- Polyclonal
- Antigen
- NALP3 antibody was raised against a 16 amino acid peptide from near the amino terminusof human NALP3.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Submitted references Conventional Study on Novel Dicationic Ionic Liquid Inclusion with β-Cyclodextrin.
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3.
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation.
Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties.
Mohamad S, Surikumaran H, Raoov M, Marimuthu T, Chandrasekaram K, Subramaniam P
International journal of molecular sciences 2011;12(9):6329-45
International journal of molecular sciences 2011;12(9):6329-45
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3.
Kanneganti TD, Ozören N, Body-Malapel M, Amer A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, Akira S, Núñez G
Nature 2006 Mar 9;440(7081):233-6
Nature 2006 Mar 9;440(7081):233-6
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.
Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J
Immunity 2004 Mar;20(3):319-25
Immunity 2004 Mar;20(3):319-25
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation.
Chamaillard M, Girardin SE, Viala J, Philpott DJ
Cellular microbiology 2003 Sep;5(9):581-92
Cellular microbiology 2003 Sep;5(9):581-92
Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties.
O'Connor W Jr, Harton JA, Zhu X, Linhoff MW, Ting JP
Journal of immunology (Baltimore, Md. : 1950) 2003 Dec 15;171(12):6329-33
Journal of immunology (Baltimore, Md. : 1950) 2003 Dec 15;171(12):6329-33
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of NALP3 in K562 cell lysate with NALP3 antibody Cat.-No AP30578PU-N at 1 ?g/ml (A) in the absence and (B) in the presence of blocking peptide.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunofluorescence of NALP3 in K562 cells with NALP3 antibody Cat.-No AP30578PU-N at 20 ?g/ml.
